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Mixed micelles loaded with hesperidin protect against acetaminophen induced acute liver injury by inhibiting the mtDNA-cGAS-STING pathway
期刊论文
COLLOIDS AND SURFACES B-BIOINTERFACES, 2024, 卷号: 233, 页码: 12
作者:
Dong, Kehong
;
Sun, Yuxuan
;
Gao, Xintao
;
Wang, Jing
;
Wu, Xiaochen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/04/07
Acetaminophen
Liver injury
Hesperidin
MtDNA
CGAS-STING
Fluorescent probes for biomolecule detection under environmental stress
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 431, 页码: 40
作者:
Han, Xiaoyue
;
Wang, Yue
;
Huang, Yan
;
Wang, Xiaoyan
;
Choo, Jaebum
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Fluorescent probe
Biomolecule
Environmental stress
Physiological
pathological processes
Chemical exposure
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
Clinical application of pyrrole-hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans
期刊论文
ARCHIVES OF TOXICOLOGY, 2020, 页码: 7
作者:
Ma, Jiang
;
Zhang, Wei
;
He, Yisheng
;
Zhu, Lin
;
Zhang, Chunyuan
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
Pyrrolizidine alkaloids
Liver injury
Diagnostic biomarkers
Pyrrole-hemoglobin adducts
Pyrrole-plasma protein adducts
Research progress on the protective effects of licorice-derived 18 beta-glycyrrhetinic acid against liver injury
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Wu, Shou-yan
;
Wang, Wen-jie
;
Dou, Jin-hui
;
Gong, Li-kun
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
18 beta-glycyrrhetic acid
licorice preparation
liver injury
glycyrrhetinic acid target
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury
期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:
Hu, Dan-Dan
;
Zhao, Qi
;
Cheng, Yan
;
Xiao, Xue-Rong
;
Huang, Jian-Feng
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/03/26
liver injury
metabolomics
PPAR alpha
acylcarnitines
Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 174, 页码: 353-362
作者:
Liang, Shengxian
;
Liang, Shaojun
;
Yin, Nuoya
;
Faiola, Francesco
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/10/21
Thyroid hormones (THs)
Polybrominated diphenyl ethers BDE-47/209
Human embryonic stem cells (ESCs)
Developmental hepatotoxicity
Endocrine-disrupting chemicals (EDCs)
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice
期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:
Wang, Yi-Kun
;
Yang, Xiao-Nan
;
Liang, Wei-Qing
;
Xiao, Yao
;
Zhao, Qi
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/07/29
Pazopanib
hepatotoxicity
metabolomics
oxidative stress
ultra-performance liquid chromatography-electrospray ion source-quadrupole
time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)
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