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BRD4 Targets the KEAP1-Nrf2-G6PD Axis and Suppresses Redox Metabolism in Small Cell Lung Cancer 期刊论文
ANTIOXIDANTS, 2022, 卷号: 11
作者:  Lv, Yang;  Lv, Xiaotong;  Zhang, Jiahui;  Cao, Guozhen;  Xu, Changzhi
收藏  |  浏览/下载:30/0  |  提交时间:2022/05/16
Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma 期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:  Chen, Zi-qi;  Cao, Zhe-rui;  Wang, Yi;  Zhang, Xi;  Xu, Lan
收藏  |  浏览/下载:56/0  |  提交时间:2021/12/16
CYH33  MYC  P300  BET  B cell lymphoma  PI3K  
Discovery of High-Affinity Inhibitors of the BPTF Bromodomain 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12075-12088
作者:  Lu, Tian
收藏  |  浏览/下载:39/0  |  提交时间:2021/11/04
Multi-omics characterization of WNT pathway reactivation to ameliorate BET inhibitor resistance in liver cancer cells 期刊论文
GENOMICS, 2021, 卷号: 113, 期号: 3, 页码: 1057-1069
作者:  Liu, Yuwei;  Xue, Mengzhu;  Cao, Danyan;  Qin, Lihuai;  Wang, Ying
收藏  |  浏览/下载:33/0  |  提交时间:2021/08/17
Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 185, 页码: 14
作者:  Wu, Qian;  Chen, Dan-Qi;  Sun, Lin;  Huan, Xia-Juan;  Bao, Xu-Bin
收藏  |  浏览/下载:118/0  |  提交时间:2021/05/24
Overcoming immune resistance by sequential prodrug nanovesicles for promoting chemoimmunotherapy of cancer 期刊论文
NANO TODAY, 2021, 卷号: 36, 页码: 12
作者:  Zhou, Fengqi;  Gao, Jing;  Xu, Zhiai;  Li, Tianliang;  Gao, Ang
收藏  |  浏览/下载:27/0  |  提交时间:2021/06/11
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian
收藏  |  浏览/下载:31/0  |  提交时间:2021/05/24
Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer 期刊论文
ADVANCED SCIENCE, 2021, 页码: 12
作者:  Sun, Fang;  Zhu, Qiurong;  Li, Tianliang;  Saeed, Madiha;  Xu, Zhiai
收藏  |  浏览/下载:47/0  |  提交时间:2021/05/24
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan
收藏  |  浏览/下载:21/0  |  提交时间:2021/05/24
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan
收藏  |  浏览/下载:24/0  |  提交时间:2020/12/24


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