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Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:  Fu, Weitao;  Zhang, Minkui;  Liao, Jianing;  Tang, Qing;  Lei, Yixuan
收藏  |  浏览/下载:56/0  |  提交时间:2022/03/21
Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 7
作者:  Wang, Yi;  Fang, Sui;  Wu, Yan
收藏  |  浏览/下载:110/0  |  提交时间:2021/08/17
Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton
收藏  |  浏览/下载:44/0  |  提交时间:2021/08/17
Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
作者:  Lu, Yan;  Liu, Hongyue;  Yang, Dehua;  Zhong, Li;  Xin, Ye
收藏  |  浏览/下载:25/0  |  提交时间:2021/08/17
Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan
收藏  |  浏览/下载:83/0  |  提交时间:2021/06/11
Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan
收藏  |  浏览/下载:82/0  |  提交时间:2021/06/11
Structural insights into the human D1 and D2 dopamine receptor signaling complexes 期刊论文
CELL, 2021, 卷号: 184, 期号: 4, 页码: 931-+
作者:  Zhuang, Youwen;  Xu, Peiyu;  Mao, Chunyou;  Wang, Lei;  Krumm, Brian
收藏  |  浏览/下载:22/0  |  提交时间:2021/05/24
Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening 期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11
作者:  Wang, Yuwei;  Tang, Shuai;  Lai, Huanling;  Jin, Ruyi;  Long, Xu
收藏  |  浏览/下载:53/0  |  提交时间:2020/12/24
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines 期刊论文
FEBS JOURNAL, 2020, 页码: 18
作者:  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Xiong, Muya;  Zhu, Mengying
收藏  |  浏览/下载:87/0  |  提交时间:2020/12/24
Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 5
作者:  Hu, Chujiao;  Zuo, Yu;  Liu, Jingqiu;  Xu, Heng;  Liao, Weike
收藏  |  浏览/下载:41/0  |  提交时间:2020/07/01


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