CORC

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CORC

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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
收藏  |  浏览/下载：11/0  |  提交时间：2024/04/07
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：25/0  |  提交时间：2022/01/04
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei
收藏  |  浏览/下载：53/0  |  提交时间：2021/05/24
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:  Zhang, Ning;  Tian, Yu-Nan;  Zhou, Li-Na;  Li, Meng-Zhu;  Chen, Hua-Dong
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
Overcoming immune resistance by sequential prodrug nanovesicles for promoting chemoimmunotherapy of cancer 期刊论文
NANO TODAY, 2021, 卷号: 36, 页码: 12
作者:  Zhou, Fengqi;  Gao, Jing;  Xu, Zhiai;  Li, Tianliang;  Gao, Ang
收藏  |  浏览/下载：26/0  |  提交时间：2021/06/11
Out-of-the-Box Nanocapsules Packed with On-Demand Hydrophobic Anticancer Drugs for Lung Targeting, Esterase Triggering, and Synergy Therapy 期刊论文
ADVANCED HEALTHCARE MATERIALS, 2021
作者:  Zhao, Di;  Jiang, Kai;  Wang, Yuqi;  Cheng, Jin;  Mo, Fangli
收藏  |  浏览/下载：124/0  |  提交时间：2021/03/15
DeepDRK: a deep learning framework for drug repurposing through kernel-based multi-omics integration 期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 5
作者:  Wang, Yongcui;  Yang, Yingxi;  Chen, Shilong;  Wang, Jiguang
收藏  |  浏览/下载：31/0  |  提交时间：2021/11/18
Effects of 8-Amino-Isocorydine, a Derivative of Isocorydine, on Gastric Carcinoma Cell Proliferation and Apoptosis 期刊论文
Current Therapeutic Research, 2021, 期号: 94, 页码: 100624
作者:  lei song;  junxi liu
收藏  |  浏览/下载：10/0  |  提交时间：2021/11/25
Paclitaxel-nanoparticles-loaded double network hydrogel for local treatment of breast cancer after surgical resection 期刊论文
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2020, 卷号: 114, 页码: 10
作者:  Wang, Mingchao;  Chen, Jian;  Li, Wenjun;  Zang, Fan;  Liu, Xuexia
收藏  |  浏览/下载：50/0  |  提交时间：2021/06/21
Mild-heat-inducible sequentially released liposomal complex remodels the tumor microenvironment and reinforces anti-breast-cancer therapy 期刊论文
BIOMATERIALS SCIENCE, 2020, 卷号: 8
作者:  Qin, Yue;  Liu, Tingting;  Guo, Mengfei;  Liu, Yuping;  Liu, Congyan
收藏  |  浏览/下载：22/0  |  提交时间：2020/11/26

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