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Real-time structural signatures of protein allostery by electrically- and mechanically-coupled sensing 期刊论文
NANO TODAY, 2024, 卷号: 55, 页码: 10
作者:  Zhang, Mingkun;  Zheng, Zhi;  Zhou, Jin;  Ding, Qihan;  Long, Mian
收藏  |  浏览/下载:2/0  |  提交时间:2024/03/25
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
收藏  |  浏览/下载:4/0  |  提交时间:2024/04/07
The allosteric gating mechanism of the MthK channel 期刊论文
NATIONAL SCIENCE REVIEW, 2022, 卷号: 9
作者:  Guan, Fenghui;  Li, Tianyu;  Dong, Wei;  Guo, Rui;  Chai, Hao
收藏  |  浏览/下载:14/0  |  提交时间:2022/12/23
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer 期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
作者:  Li N(李宁);  Zhang XY(张晓宇);  Zhou J(周瑾);  Li W(李旺);  Shu XY(舒芯钰)
收藏  |  浏览/下载:27/0  |  提交时间:2022/10/23
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing
收藏  |  浏览/下载:25/0  |  提交时间:2022/01/18
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui
收藏  |  浏览/下载:27/0  |  提交时间:2022/01/04
Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125
作者:  Zhang, Huimin;  He, Jixiao;  Hu, Guang;  Zhu, Fei;  Jiang, Hao
收藏  |  浏览/下载:36/0  |  提交时间:2022/01/04
Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains 期刊论文
IMMUNITY, 2021, 卷号: 54, 期号: 10, 页码: 2218-+
作者:  Song, Bin;  Chen, Yun;  Liu, Xin;  Yuan, Fei;  Tan, Eddie Yong Jun
收藏  |  浏览/下载:23/0  |  提交时间:2021/12/01
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:  Xie, Hong-Xu;  Zhang, Juan;  Li, Yue;  Zhang, Jin-He;  Liu, Shan-Kui
收藏  |  浏览/下载:69/0  |  提交时间:2021/11/04
Structures of full-length glycoprotein hormone receptor signalling complexes 期刊论文
NATURE, 2021, 页码: 24
作者:  Duan, Jia;  Xu, Peiyu;  Cheng, Xi;  Mao, Chunyou;  Croll, Tristan
收藏  |  浏览/下载:53/0  |  提交时间:2021/11/04


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