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科研机构
上海药物研究所 [3]
重庆大学 [2]
西安交通大学 [1]
内容类型
期刊论文 [6]
发表日期
2021 [1]
2018 [2]
2017 [3]
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New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3117-3125
作者:
Liu, Wenwen
;
Wang, Huan
;
Li, Xiaokang
;
Xu, Yixiang
;
Zhang, Jian
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  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
Depression
Cognitive impairment
Multitarget-directed ligand
5-HT1A agonist
5-HT reuptake inhibition
ChE inhibition
Efficacy and tolerability of different doses of three new antidepressants for treating major depressive disorder: A PRISMA-compliant meta-analysis
期刊论文
JOURNAL OF PSYCHIATRIC RESEARCH, 2018, 卷号: 96, 页码: 247-259
作者:
He, Hairong
;
Wang, Wei
;
Lyu, Jun
;
Zheng, Jie
;
Guo, Liyang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/11/26
Vortioxetine
Vilazodone
Major depressive disorder
Levomilnacipran
Tolerability
Novel Vilazodone Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 2708-2721
作者:
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Alzheimer's disease
depression
multitarget-directed ligand
ChE inhibition
5-HT1A agonist
5-HT reuptake inhibition
Revealing vilazodone's binding mechanism underlying its partial agonism to the 5-HT1A receptor in the treatment of major depressive disorder
期刊论文
2017, 卷号: 19, 页码: 28885-28896
作者:
Zheng, Guoxun[1,2,3]
;
Xue, Weiwei[1,2]
;
Yang, Fengyuan[1,2,3]
;
Zhang, Yang[1,2,3]
;
Chen, Yuzong[4]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/11/28
Revealing vilazodone's binding mechanism underlying its partial agonism to the 5-HT receptor in the treatment of major depressive disorder.
期刊论文
2017, 卷号: 19
作者:
Zheng, Guoxun[1]
;
Xue, Weiwei
;
Yang, Fengyuan
;
Zhang, Yang
;
Chen, Yuzong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/29
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