×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [32]
西北高原生物研究所 [29]
西安交通大学 [10]
山东大学 [3]
合肥物质科学研究院 [3]
兰州大学 [2]
更多...
内容类型
期刊论文 [88]
学位论文 [3]
专利 [1]
发表日期
2022 [1]
2020 [3]
2019 [6]
2018 [11]
2017 [4]
2016 [8]
更多...
学科主题
computer s... [2]
Chemistry ... [1]
biochemist... [1]
chemistry [1]
crystallog... [1]
mathematic... [1]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共92条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
The reversal of anti-HER2 resistance in advanced HER2-positive breast cancer using apatinib: two cases reports and literature review
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2022
作者:
He, Libin
;
Shen, Xiabo
;
Liu, Yiyuan
;
Gao, Lu
;
Wu, Jiayi
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
Advanced human epidermal growth factor receptor 2-positive breast cancer (advanced HER2-positive breast cancer)
apatinib
case report
Construction of a novel bispecific fusion protein to enhance targeting for pancreatic cancer imaging
期刊论文
BIOMATERIALS, 2020, 期号: 255, 页码: 120161
作者:
Wang, Qian
;
Yan, Hao
;
Wang, Zihua
;
Li, Zhangfu
;
Li, Dan
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/09/07
Bispecific targeting
Fusion protein
Antibody
Molecular imaging
Pancreatic cancer
Discovery of a highly selective VEGFR2 kinase inhibitor CHMFL-VEGFR2-002 as a novel anti-angiogenesis agent
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10
作者:
Jiang, Zongru
;
Wang, Li
;
Liu, Xuesong
;
Chen, Cheng
;
Wang, Beilei
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/11/26
Cancer
VEGFR2 kinase
Kinase inhibitor
Angiogenesis
Inhibitor selectivity
Synthesis and evaluation of new thiourea derivatives as antitumor and antiangiogenic agents
期刊论文
TETRAHEDRON LETTERS, 2020, 卷号: 61, 期号: 40
作者:
Bai, Wenjing
;
Ji, Jianxin
;
Huang, Qiang
;
Wei, Wei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/11/25
Thiourea derivatives
Antitumor
Antiangiogenesis
RTK inhibitors
Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas
期刊论文
BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13
作者:
Zhang, Qing
;
Liu, Jian-He
;
Liu, Jing-Li
;
Qi, Chun-Ting
;
Yan, Lei
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2020/07/01
Receptor tyrosine kinases (RTKs)
Activation and function
Clear cell renal cell carcinomas (ccRCCs)
Targeted therapy
PDGFR beta
Stroma cells
Exploring binding mechanisms of VEGFR2 with three drugs lenvatinib, sorafenib, and sunitinib by molecular dynamics simulation and free energy calculation
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 5, 页码: 934-948
作者:
Wang, Yu
;
Peng, Cheng
;
Wang, Guimin
;
Xu, Zhijian
;
Luo, Yongfeng
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
hydrophobic contact scanning
MM
GBSA
molecular dynamics simulation
VEGFR2-drugs interaction
Discovery of 6-Arylurea-2-arylbenzoxazole and 6-Arylurea-2-arylbenzimidazole Derivatives as Angiogenesis Inhibitors: Design, Synthesis and in vitro Biological Evaluation
期刊论文
CHEMMEDCHEM, 2019, 卷号: 14, 期号: 13
作者:
Zi, Mengli
;
Liu, Feifei
;
Wu, Di
;
Li, Ke
;
Zhang, Da
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/04
anti-angiogenesis
benzimidazoles
benzoxazoles
VEGFR-2 kinase inhibitors
Discovery of novel anti-angiogenesis agents. Part 10: Multi-target inhibitors of VEGFR-2, Tie-2 and EphB4 incorporated with 1,2,3-triazol.
期刊论文
European journal of medicinal chemistry, 2019, 卷号: 163, 页码: 1-9
作者:
Pan Xiaoyan
;
Liang Liyuan
;
Si Ru
;
Wang Jin
;
Zhang Qingqing
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/11/19
Anti-angiogenic agents
Triple RTK inhibitors
1,2,3-Triazole
DFG-binding group
Multi-target
Design, synthesis and biological evaluation of novel 4-anilinoquinazoline derivatives as hypoxia-selective EGFR and VEGFR-2 dual inhibitors
期刊论文
2019, 卷号: 181, 页码: 111552
作者:
Wei Huiqiang
;
Duan Yuqing
;
Gou Wenfeng
;
Cui Jie
;
Ning Hongxin
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
3-Nitro-1
2
4-triazole
EGFR
Hypoxia
Tyrosine kinase inhibitor
VEGFR-2
Vandetanib
Natural products as important tyrosine kinase inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 111664
作者:
Yin, Bo
;
Fang, Dong-Mei
;
Zhou, Xian-Li
;
Gao, Feng
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/11/04
Natural products
Tyrosine kinase inhibitors
Bcr-Abl
JAK-STAT
EGFR
VEGFR
IGF-1R
c-Met(HGFR)
PDGFR
FGFR
HER-2/neu
©版权所有 ©2017 CSpace - Powered by
CSpace