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CORC

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Discovery of isopenicin A, a meroterpenoid as a novel inhibitor of tubulin polymerization 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020
作者:  Chen, Lin;  Fan, Dong-Mei;  Tang, Jian-Wei;  An, Tao;  Li, Xue
收藏  |  浏览/下载：47/0  |  提交时间：2021/01/05
1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 448-456
作者:  Jiang, Junhang;  Zhang, Hao;  Wang, Chongqing;  Zhang, Qingsen;  Fang, Shaoyu
收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li
收藏  |  浏览/下载：69/0  |  提交时间：2019/07/29
3, 9-di-O-substituted coumestrols incorporating basic amine side chains act as novel apoptosis inducers with improved pharmacological selectivity 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 85
作者:  Luo, Guoshun;  Tang, Zhengpu;  Li, Xinyu;  Hou, Qiangqiang;  Chen, Yu
收藏  |  浏览/下载：17/0  |  提交时间：2019/12/05
Tubulin colchicine site binding agent LL01 displays potent antitumor efficiency both in vitro and in vivo with suitable drug-like properties 期刊论文
Investigational New Drugs, 2019
作者:  Wu J.-D.;  Cui Y.-J.;  Zhou Y.-G.;  Tang L.-Q.;  Zhang C.-M.
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/11
Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site 期刊论文
Bioorganic Chemistry, 2019, 卷号: Vol.85, 页码: 49-59
作者:  Wenlong Li;  Honghao Sun;  Feijie Xu;  Wen Shuai;  Jie Liu
收藏  |  浏览/下载：30/0  |  提交时间：2019/12/13
The Structure of MT189-Tubulin Complex Provides Insights into Drug Design 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 9, 页码: 1069-1073
作者:  Li, Zhongping;  Ma, Lingling;  Wu, Chengyong;  Meng, Tao;  Ma, Lanping
收藏  |  浏览/下载：8/0  |  提交时间：2020/07/01
Synthesis, Crystal Structure and Bioactivity of Ethyl 1-((2-Bromophenyl)carbamoyl)-2-(3,4,5-trimethoxyphenyl) cyclopropanecarboxylate 期刊论文
结构化学, 2019, 卷号: 38.0, 期号: 012, 页码: 2070-2076
作者:  Jia H(贾辉);  Zhong HY(钟涵宇);  Zhang JY(张敬一)
收藏  |  浏览/下载：11/0  |  提交时间：2021/02/02
The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors 期刊论文
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:  Wang, Xinyi;  Ai, Jing;  Liu, Hongyan;  Peng, Xia;  Chen, Hui
收藏  |  浏览/下载：135/0  |  提交时间：2019/01/08
New microtubulin inhibitor MT189 suppresses angiogenesis via the JNK-VEGF/VEGFR2 signaling axis 期刊论文
CANCER LETTERS, 2018, 卷号: 416, 页码: 57-65
作者:  Xu, Lin;  Wang, Wei;  Meng, Tao;  Ma, Lan-Ping;  Tong, Lin-Jiang
收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08

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