CORC

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CORC

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Triptolide analog LLDT-8 ameliorates psoriasis-like dermatitis in BALB/c mice via suppressing the IL-36 alpha signaling pathway 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:  Qi, Qing;  Li, Qian;  Zhu, Hongwen;  Lu, Huimin;  Yang, Xiaoqian
收藏  |  浏览/下载：72/0  |  提交时间：2021/08/17
CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1386-1392
作者:  Xu, Ye;  Zhang, Yi-fan;  Chen, Xiao-yan;  Zhong, Da-fang
收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08
Synthesis, Characterization, and Evaluation of Triptolide Cell-Penetrating Peptide Derivative for Transdermal Delivery of Triptolide 期刊论文
MOLECULAR PHARMACEUTICS, 2018, 卷号: 15, 页码: 560-570
作者:  Tian, Tian;  Song, Yuming;  Li, Ke;  Sun, Yuming;  Wang, Qing
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/02
cyp3a4inducerandinhibitorstronglyaffectthepharmacokineticsoftriptolideanditsderivativeinrats 期刊论文
actapharmacologicasinica, 2018, 卷号: 039, 期号: 008, 页码: 1386
作者:  Xu Ye;  Zhang Yifan;  Chen Xiaoyan;  Zhong Dafang
收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01
Critical Role of Hepatic Cyp450 sin the Testis-Specific Toxicity of (5R)-5-Hydroxytriptolide in C57BL/6 Mice 期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:  Yu, Cunzhi;  Li, Yu;  Liu, Mingxia;  Gao, Man;  Li, Chenggang
收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08
(5R)-5-hydroxytriptolide ameliorates lupus nephritis in MRL/lpr mice by preventing infiltration of immune cells 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2017, 卷号: 312, 期号: 4, 页码: F769-F777
作者:  Zhang, Lu-yao;  Li, Heng;  Wu, Yan-wei;  Cheng, Lei;  Yan, Yu-xi
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08
Valuable model for clinical trail-System Toxicological Studies on Active Components in derivatives of Lei-Gong-Teng from Traditional Chinese Medicines 会议论文
作者:  Ren J(任进)
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08
Dephosphorylation of Tak1 at Ser412 greatly contributes to the spermatocyte-specific testis toxicity induced by (5R)-5-hydroxytriptolide in C57BL/6 mice 期刊论文
TOXICOLOGY RESEARCH, 2016, 卷号: 5, 期号: 2, 页码: 594-601
作者:  Qi, Xinming;  Li, Chunzhu;  Wu, Chunyong;  Yu, Cunzhi;  Liu, Mingxia
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08
Determination of pK(a) values of a triptolide derivative and its impurities by pressure-assisted capillary electrophoresis 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014, 卷号: 88, 页码: 22-26
作者:  Wang, Jian-Ling;  Xu, Xue-Jiao;  Chen, Dong-Ying
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08
(5R)-5-hydroxytriptolide (LLDT-8), a novel immunosuppressant in clinical trials, exhibits potent antitumor activity via transcription inhibition 期刊论文
CANCER LETTERS, 2012, 卷号: 324, 期号: 1, 页码: 75-82
作者:  Wang, Lei;  Xu, Yongping;  Fu, Li;  Li, Yuanchao;  Lou, Liguang
收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08

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