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Low molecular weight fucoidan restores diabetic endothelial glycocalyx by targeting neuraminidase2: A new therapy target in glycocalyx shedding
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2024, 页码: 17
作者:
Li, Zhi
;
Wu, Ning
;
Wang, Jing
;
Yue, Yang
;
Geng, Lihua
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/04/07
diabetic vascular complication
glycocalyx
insulin resistance
LMWF
NEU2
Effects of glyphosate exposure on gut-liver axis: Metabolomic and mechanistic analysis in grass carp (Ctenopharyngodon idellus)
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 902, 页码: 12
作者:
Yan, Biao
;
Sun, Yumiao
;
Fu, Kaiyu
;
Zhang, Yindan
;
Lei, Lei
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
Glyphosate
Metabolomics
Grass carp
Gut-Liver axis
Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN
期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:
Liu, Bin
;
Jiang, Shangwen
;
Li, Min
;
Xiong, Xuelian
;
Zhu, Mingrui
收藏
  |  
浏览/下载:113/0
  |  
提交时间:2019/01/08
Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632
作者:
Zhang, Mei
;
Xie, Zhi-fu
;
Zhang, Run-tao
;
Chen, Da-kai
;
Gu, Min
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  |  
浏览/下载:46/0
  |  
提交时间:2019/01/08
non-alcoholic fatty liver disease
AMP-activated protein kinase
AMPK activator
homogeneous time-resolved fluorescence
metabolic disorders
ob/ob mice
HCBP6 upregulates human SREBP1c expression by binding to C/EBP beta-binding site in the SREBP1c promoter
期刊论文
BMB REPORTS, 2018, 卷号: 51, 页码: 33-38
作者:
Yang, Xueliang
;
Han, Ming
;
Liu, Shunai
;
Yuan, Xiaoxue
;
Liu, Xiaojing
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/19
HCBP6
SREBP1c
Triglyceride homeostasis
Transcription factor
C/EBP beta
PPAR alpha activation protects against cholestatic liver injury
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 9967
作者:
Zhao, Qi
;
Yang, Rui
;
Wang, Jing
;
Hu, Dan-Dan
;
Li, Fei
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  |  
浏览/下载:42/0
  |  
提交时间:2017/10/23
Primary Biliary-cirrhosis
Bile-acid Homeostasis
Receptor-alpha
Ursodeoxycholic Acid
Cholesterol 7-alpha-hydroxylase
Beta-oxidation
Fenofibrate
Therapy
Mice
Hepatotoxicity
Targeting hepatic TRAF1-ASK1 signaling to improve inflammation, insulin resistance, and hepatic steatosis
期刊论文
Journal of Hepatology, 2016, 卷号: 64, 期号: 6, 页码: 1365-1377
作者:
Xiang, Mei
;
Wang, Pi-Xiao
;
Wang, Ai-Bing
;
Zhang, Xiao-Jing
;
Zhang, Yaxing
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/23
TRAF1
Tumor necrosis factor receptor-associated factor 1
NAFLD
non-alcoholic fatty liver disease
HFD
high fat diet
KO
knockout
LTG
liver-specific TRAF1 transgenic
NTG
non-transgenic
TNFR
Tumor necrosis factor receptor
GTT
glucose tolerance test
ITT
insulin tolerance test
AUC
areas under the curve
TG
triglyceride
TC
total cholesterol
NEFA
non-esterified fatty acid
HOMA-IR
homeostasis model assessment of the IR index
ALT
alanine amino transferase
AST
aspartate amino transferase
ANOVA
analysis of variance
LW/BW
liver weight/body weight
TRAF1
Hepatic steatosis
Inflammation
Insulin resistance
ASK1
HCBP6 Modulates Triglyceride Homeostasis in Hepatocytes Via the SREBP1c/FASN Pathway
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2015, 卷号: 116, 期号: 10, 页码: 2375-2384
作者:
Gao, LL
;
Li, M
;
Wang, Q
;
Liu, SA
;
Zhang, JQ
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/01/09
FATTY ACID
GENE EXPRESSION
LIPASE
HEPATIC
NUCLEAR RECEPTORS
SREBP
TRIGLYCERIDES
MicroRNA-122
Activation of the farnesoid X receptor promotes triglyceride lowering by suppressingPhospholipase A2 G12B expression in hyperlipidemic mice
会议论文
Keystone Symposia Conference- The Crossroads of Lipid Metabolism and Diabetes, 丹麦哥本哈根
作者:
Qingli Liu
;
Meng Yang
;
Renzhong Liu
;
Yang Lei
;
Xuekun Fu
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2016/01/27
Intracellular role of exchangeable apolipoproteins in energy homeostasis, obesity and non‐alcoholic fatty liver disease
期刊论文
Biological Reviews, 2015, 卷号: 90, 期号: 2, 页码: 367-376
作者:
Wu, Chen-Lu
;
Zhao, Shui-Ping*
;
Yu, Bi-Lian
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
apolipoprotein
triglyceride
adipocyte
hepatocyte
obesity
non‐alcoholic fatty liver disease
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