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上海药物研究所 [13]
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Downregulation of hsa-miR-203 in peripheral blood and wound margin tissue by negative pressure wound therapy contributes to wound healing of diabetic foot ulcers
期刊论文
MICROVASCULAR RESEARCH, 2022, 卷号: 139
作者:
Liu, Lei
;
Chen, Ruofei
;
Jia, Zeguo
;
Li, Xueting
;
Tang, Ying
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/01/10
Type 2 diabetes
Foot ulcers
Negative pressure wound therapy
Keratinocytes
Hsa-miR-203
p63
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Ren, Yu-ran
;
Ye, Yang-liang
;
Feng, Ying
;
Xu, Ti-fei
;
Shen, Yu
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  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
SL010110
gluconeogenesis
primary mouse hepatocytes
PEPCK1
acetylation
degradation
DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Huang, Jun-shang
;
Guo, Bin-bin
;
Wang, Gai-hong
;
Zeng, Li-min
;
Hu, You-hong
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  |  
浏览/下载:57/0
  |  
提交时间:2020/12/24
type 2 diabetes
DGAT1 inhibitors
pancreatic beta-cells
apoptosis
ER stress
inflammation
Computational Bioinformatics and Machine Learning Models to Identify the Diseasome and Neurological Disease Comorbidities
学位论文
中国科学院自动化研究所: 中国科学院大学, 2020
作者:
Md Habibur Rahman
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  |  
浏览/下载:18/0
  |  
提交时间:2020/07/15
疾病共病鉴定
生存分析
生物信息学
机器学习
2 型糖尿病
神经系统疾病
胶质母细胞瘤
通路
基因本体
蛋白质
A Network-Based Bioinformatics Approach to Identify Molecular Biomarkers for Type 2 Diabetes that Are Linked to the Progression of Neurological Diseases
期刊论文
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2020, 卷号: 17, 期号: 3, 页码: 25
作者:
Rahman, Md Habibur
;
Peng, Silong
;
Hu, Xiyuan
;
Chen, Chen
;
Rahman, Md Rezanur
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  |  
浏览/下载:35/0
  |  
提交时间:2020/04/07
bioinformatics
computational biology
gene ontology
protein
pathways
type 2 diabetes
neurological disease
Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268
作者:
Liu, Xia
;
Wang, Wei
;
Chen, Hua-li
;
Zhang, Hai-yan
;
Zhang, Nai-xia
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  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Alzheimer's disease
type 2 diabetes
APP/PS1 transgenic mice
metabolomics
NMR
glucose metabolism dysfunctions
Saxagliptin alters bile acid profiles and yields metabolic benefits in drug-naive overweight or obese type 2 diabetes patient
期刊论文
JOURNAL OF DIABETES, 2019, 页码: 11
作者:
Li, Wen
;
Liu, Ruixin
;
Li, Xuelin
;
Tao, Bei
;
Zhai, Nan
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  |  
浏览/下载:74/0
  |  
提交时间:2019/12/02
bile acids
dipeptidyl peptidase-4 inhibitor
obesity
saxagliptin
type 2 diabetes
All-atom structure ensembles of islet amyloid polypeptides determined by enhanced sampling and experiment data restraints
期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2019, 卷号: 87, 期号: 7, 页码: 541-550
作者:
Su, Xinyue
;
Wang, Ke
;
Liu, Na
;
Chen, Jiawen
;
Li, Yong
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  |  
浏览/下载:73/0
  |  
提交时间:2019/10/14
aggregation
chemical shift restraint
islet amylod polypeptide
metadynamics
Multi-Level Comparative Framework Based on Gene Pair-Wise Expression Across Three Insulin Target Tissues for Type 2 Diabetes
期刊论文
FRONTIERS IN GENETICS, 2019, 卷号: 10, 页码: 16
作者:
Sun, Shaoyan
;
Sung, Fengnan
;
Wang, Yong
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  |  
浏览/下载:71/0
  |  
提交时间:2020/01/10
type 2 diabetes
gene pairwise expression
dysfunctional interactions
multi-level analysis
random walk with restart
Aldosterone induced up-expression of ICAM-1 and ET-1 in pancreatic islet endothelium may associate with progression of T2D
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 512, 期号: 4, 页码: 750-757
作者:
Wang, Jinbang
;
Hu, Huiqing
;
Song, Jia
;
Yan, Fei
;
Qin, Jun
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  |  
浏览/下载:27/0
  |  
提交时间:2019/12/11
Aldosterone
Islet endothelium
ICAM-1
Endothelin-1
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