CORC

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CORC

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Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：24/0  |  提交时间：2022/01/04
The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
作者:  Ma, Liying;  Bian, Xing;  Lin, Wenchu
收藏  |  浏览/下载：40/0  |  提交时间：2020/11/30
Design, synthesis and biological evaluation of a series of novel 2-benzamide-4-(6-oxy-N-methyl-l-naphthamide)-pyridine derivatives as potent fibroblast growth factor receptor (FGFR) inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154, 页码: 9-28
作者:  Wei, Manman;  Peng, Xia;  Xing, Li;  Dai, Yang;  Huang, Ruimin
收藏  |  浏览/下载：63/0  |  提交时间：2019/01/08
Combined inhibition of PI3K delta and FLT3 signaling exerts synergistic antitumor activity and overcomes acquired drug resistance in FLT3-activated acute myeloid leukemia 期刊论文
CANCER LETTERS, 2018, 卷号: 420, 页码: 49-59
作者:  He, Ye;  Sun, Liping;  Xu, Yongping;  Fu, Li;  Li, Yun
收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08
Synergistic antiproliferative effect of chemo-phototherapy: Synthesis and photodynamic activity evaluation of novel Chlorin e6-artesunate conjugates as antiproliferative agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 页码: 4548-4551
作者:  Guo, Xiuhan;  Wang, Liu;  Wang, Shisheng;  Li, Yueqing;  Cao, Lei
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/03
HSP90 inhibitor AUY922 abrogates up-regulation of RTKs by mTOR inhibitor AZD8055 and potentiates its antiproliferative activity in human breast cancer 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2014, 卷号: 135, 期号: 10, 页码: 2462-2474
作者:  Chen, Si-Meng;  Guo, Chen-Liang;  Shi, Jia-Jie;  Xu, Yi-Chao;  Chen, Yi
收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08
The discovery and optimization of novel dual inhibitors of topoisomerase ii and histone deacetylase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 22, 页码: 6981-6995
作者:  Zhang, Xuan;  Bao, Bin;  Yu, Xiuhua;  Tong, Linjiang;  Luo, Yu
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
S9, a Novel Anticancer Agent, Exerts Its Anti-Proliferative Activity by Interfering with Both PI3K-Akt-mTOR Signaling and Microtubule Cytoskeleton 期刊论文
PLOS ONE, 2009, 卷号: 4, 期号: 3
作者:  Zhang, Chao;  Yang, Na;  Yang, Chun-hao;  Ding, Hua-sheng;  Luo, Cheng
收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08

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