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Hypoxia-inducible factor 1-alpha is a driving mechanism linking chronic obstructive pulmonary disease to lung cancer
期刊论文
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12
作者:
Xu, Yuan-rui
;
Wang, An-long
;
Li, Ya-qing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
chronic obstructive pulmonary disease
lung cancer
non-small cell lung cancer
hypoxia-inducible factor 1-alpha
hypoxia-inducible factor 1
Bronchial epithelial SIRT1 deficiency exacerbates cigarette smoke induced emphysema in mice through the FOXO3/PINK1 pathway
期刊论文
EXPERIMENTAL LUNG RESEARCH, 2022
作者:
Jiang, Hui
;
Jiang, Yaona
;
Xu, Yuanri
;
Yuan, Dong
;
Li, Yaqing
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2022/03/21
COPD
FOXO3
mitophagy
PINK1
SIRT1
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Chen, Cheng
;
Ren, Yong-mei
;
Zhu, Jian-zhong
;
Chen, Jia-li
;
Feng, Zhe-ling
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/01/04
Ainsliadimer C
interleukin-1 beta
macrophages
NLRP3 inflammasome
Sirtuin 1
adipose tissue inflammation
obesity
metabolic disorders
EX-527
dexamethasone
Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403
作者:
Li, Chunpu
;
Hu, Sha-Sha
;
Yang, Lisheng
;
Wang, Min
;
Long, Jian-Dong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/05/24
SIRT1
inhibitor
structure-activity relationship
interaction
deacetylase
Senescence associated long non-coding RNA 1 regulates cigarette smoke-induced senescence of type II alveolar epithelial cells through sirtuin-1 signaling
期刊论文
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2021, 卷号: 49
作者:
Yuan, Dong
;
Liu, Yuanshun
;
Li, Mengyu
;
Zhou, Hongbin
;
Cao, Liming
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/03/15
Chronic obstructive pulmonary disease
alveolar epithelial cells
sirtuin-1
cellular senescence
long non-coding RNA
cigarette smoke
Sleeve gastrectomy ameliorated high-fat diet (HFD)-induced non-alcoholic fatty liver disease and upregulated the nicotinamide adenine dinucleotide +/ Sirtuin-1 pathway in mice
期刊论文
ASIAN JOURNAL OF SURGERY, 2021, 卷号: 44, 期号: 1, 页码: 213-220
作者:
Hua, Rong
;
Wang, Guan-Zhen
;
Shen, Qi-Wei
;
Yang, Ye-Ping
;
Wang, Meng
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
NAD
NAFLD
NRK1
SIRT1
Sleeve gastrectomy
S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis
期刊论文
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2021, 卷号: 11, 期号: 3, 页码: 697-724
作者:
Zhang, Linqiang
;
Zhang, Zhiguo
;
Li, Chengbin
;
Zhu, Tingting
;
Gao, Jing
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/05/24
NAFLD
S100A11
FOXO1
Autophagy
Lipid Metabolism
Antioxidant Activity and the Potential Mechanism of the Fruit From Ailanthus altissima Swingle
期刊论文
FRONTIERS IN VETERINARY SCIENCE, 2021, 卷号: 8, 期号: 12, 页码: 1-14
作者:
Mo, YN (Mo, Ya-nan) [1]
;
Cheng, F (Cheng, Feng) [1] , [2]
;
Yang, Z (Yang, Zhen) [1]
;
Shang, XF (Shang, Xiao-fei) [1]
;
Liang, JP (Liang, Jian-ping) [1]
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2022/03/24
Ailanthus altissima Swingle
antioxidant activityRAW264
7 cell
network pharmacology
invitro
antioxidant mechanism
Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5
期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18
作者:
Han, Haozhen
;
Li, Chunpu
;
Li, Man
;
Yang, Lisheng
;
Zhao, Sen
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/24
sirtuins
inhibitor
structure-activity relationship
deacetylase
HIF-1α-dependent miR-424 induction confers cisplatin resistance on bladder cancer cells through down-regulation of pro-apoptotic UNC5B and SIRT4
期刊论文
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1, 页码: 1-13
作者:
Meng Yu
;
Toshinori Ozaki
;
Dan Sun
;
Haotian Xing
;
Baojun Wei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/10/15
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