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上海药物研究所 [64]
大连化学物理研究所 [15]
厦门大学 [13]
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长春应用化学研究所 [11]
北京大学 [10]
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期刊论文 [193]
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Screening prolyl hydroxylase domain 2 inhibitory activity of traditional Chinese medicine by CZE-UV
期刊论文
Electrophoresis, 2022, 卷号: 15, 期号: 43, 页码: 1601-1610
作者:
Ying Zhang
;
Ming Zhao
;
Cheng-Bo Wang
;
Yu Wang
;
Nsanzamahoro Stanislas
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/11/30
capillary zone electrophoresis
derivatization reaction
PHD2 inhibitor
traditional Chinese medicine
Rapid screening of alpha-glucosidase inhibitors in Hypericum perforatum L. using bio-affinity chromatography coupled with UPLC/MS
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2022
作者:
Dong, Q
;
Hu, N
;
Yue, HL
;
Wang, HL
;
Wei, Y
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2022/12/02
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction
期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:
Xiong, Jiacheng
;
Xiang, Yusen
;
Huang, Ziming
;
Liu, Xiaohong
;
Wang, Mengge
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/12/01
SARS-CoV-2
angiotensin-converting enzyme 2 (ACE2)
spike protein receptor-binding domain (S-RBD)
structure-based virtual screening
protein-protein interaction (PPI) inhibitors
Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 6
作者:
Xiong, Fengmin
;
Ding, Xiaoyu
;
Zhang, Hao
;
Luo, Xiaomin
;
Chen, Kaixian
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
Monoacylglycerol lipase
Inhibitor
Virtual screening
Inflammation
Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 9
作者:
Yang, Longhe
;
Ji, Chunyan
;
Li, Yitian
;
Hu, Fan
;
Zhang, Fang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/10
NAAA inhibitor
atractylodin
>
anti-inflammation
microglia
traditional Chinese medicine
Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9
作者:
Han, Jie
;
Tian, Yucheng
;
Yu, Liang
;
Zhang, Qilin
;
Xu, Xi
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2020/12/24
Ubiquitination
High throughput screening
Drug discovery
USP8
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines
期刊论文
FEBS JOURNAL, 2020, 页码: 18
作者:
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Xiong, Muya
;
Zhu, Mengying
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2020/12/24
colorectal cancer
HDX-MS
inhibitor
USP25
USP28
Vismodegib
In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 6, 页码: 3265-3276
作者:
Zhao, Wenfeng
;
Xiong, Muya
;
Yuan, Xiaojing
;
Li, Minjun
;
Sun, Hongbin
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
An in vitro Fo''rster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Wang, Yu-zhe
;
Liu, Xiao
;
Way, George
;
Madarha, Vipul
;
Zhou, Qing-tong
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
SUMOylation inhibitor
WNN0605-F008
high-throughput screening
Ubc9
PIAS1
Fo''rster resonance energy transfer
surface plasmon resonance
Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors
期刊论文
NATURE, 2020, 页码: 24
作者:
Jin, Zhenming
;
Du, Xiaoyu
;
Xu, Yechun
;
Deng, Yongqiang
;
Liu, Meiqin
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
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