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上海药物研究所 [6]
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北京大学 [3]
武汉病毒研究所 [2]
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期刊论文 [26]
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Progressive polarization based reflection removal via realistic training data generation
期刊论文
PATTERN RECOGNITION, 2022, 卷号: 124, 页码: 13
作者:
Pang, Youxin
;
Yuan, Mengke
;
Fu, Qiang
;
Ren, Peiran
;
Yan, Dong-Ming
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/02/16
Deep learning
Reflection removal
Polarization
Progressive network
Convolutional neural networks
Interplay between the bacterial protein deacetylase CobB and the second messenger c-di-GMP
期刊论文
EMBO JOURNAL, 2019, 页码: 18
作者:
Xu, Zhaowei
;
Zhang, Hainan
;
Zhang, Xingrun
;
Jiang, Hewei
;
Liu, Chengxi
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
c-di-GMP
CobB
diguanylate cyclase
negative feedback loop
protein acetylation
The mimics of N-epsilon-acyl-lysine derived from cysteine as sirtuin inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 14, 页码: 2375-2378
作者:
Wang, Chun
;
Wang, Fang
;
Chen, Xiaoxue
;
Zou, Yefang
;
Zhu, Hong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
L-Cysteine
The mimics of lysine
Mechanism-based inhibitors
Sirtuin inhibitors
SIRT2 inhibitors
The NAD(+)-dependent deacetylase, Bifidobacterium longum Sir2 in response to oxidative stress by deacetylating SigH (sigma(H)) and FOXO3a in Bifidobacterium longum and HEK293T cell respectively
期刊论文
2017, 卷号: 108, 页码: 929
作者:
Guo, Qing[1]
;
Li, Shiyu[2]
;
Xie, Yajie[1]
;
Zhang, Qian[1]
;
Liu, Mengge[1]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/10
Molecular dynamics of de novo telomere heterochromatin formation in budding yeast
期刊论文
Journal of genetics and genomics, 2016, 卷号: 43, 期号: 7, 页码: 451-465
作者:
Duan, Yi-Min
;
Zhou, Bo-O.
;
Peng, Jing
;
Tong, Xia-Jing
;
Zhang, Qiong-Di
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/05/09
Telomere
Heterochromatin
Nucleosome positioning
Sir
Yku
SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2
期刊论文
CELL RESEARCH, 2016
Pan, Huize
;
Guan, Di
;
Liu, Xiaomeng
;
Li, Jingyi
;
Wang, Lixia
;
Wu, Jun
;
Zhou, Junzhi
;
Zhang, Weizhou
;
Ren, Ruotong
;
Zhang, Weiqi
;
Li, Ying
;
Yang, Jiping
;
Hao, Ying
;
Yuan, Tingting
;
Yuan, Guohong
;
Wang, Hu
;
Ju, Zhenyu
;
Mao, Zhiyong
;
Li, Jian
;
Qu, Jing
;
Tang, Fuchou
;
Liu, Guang-Hui
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2017/12/03
stem cell
aging
SIRT6
NRF2
oxidative stress
HISTONE DEACETYLASE SIRT6
LIFE-SPAN
RNA-SEQ
GENOMIC INSTABILITY
ENDOTHELIAL-CELLS
IN-VIVO
CHROMATIN
MODEL
GENE
HOMEOSTASIS
Structural basis for allosteric, substrate-dependent stimulation of sirt1 activity by resveratrol
期刊论文
Genes & development, 2015, 卷号: 29, 期号: 12, 页码: 1316-1325
作者:
Cao, Duanfang
;
Wang, Mingzhu
;
Qiu, Xiayang
;
Liu, Dongxiang
;
Jiang, Hualiang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/05/10
Histone/protein deacetylase
Resveratrol
Sirtuins
Structure
Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol
期刊论文
GENES & DEVELOPMENT, 2015, 卷号: 29, 期号: 12, 页码: 1316-1325
作者:
Cao, Duanfang
;
Wang, Mingzhu
;
Qiu, Xiayang
;
Liu, Dongxiang
;
Jiang, Hualiang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
histone/protein deacetylase
resveratrol
sirtuins
structure
Sirtuins: Nodes Connecting Aging, Metabolism and Tumorigenesis
期刊论文
current pharmaceutical design, 2014
Yao, Yisha
;
Yang, Yang
;
Zhu, Wei-Guo
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/13
Sirtuin
post-translational modification
aging
metabolism
genomic stability
apoptosis
autophagy
PANCREATIC BETA-CELLS
FATTY-ACID OXIDATION
DNA-DAMAGE RESPONSE
SACCHAROMYCES-CEREVISIAE
LIFE-SPAN
HISTONE H3
SIRT1 DEACETYLASE
CALORIE RESTRICTION
CAENORHABDITIS-ELEGANS
CELLULAR SENESCENCE
SIRT1 in cardiovascular aging
期刊论文
Clinica Chimica Acta, 2014, 卷号: 437, 页码: 106-114
作者:
Luo, Xin-Yuan
;
Qu, Shun-Lin
;
Tang, Zhi-Han
;
Zhang, Yuan
;
Liu, Mi-Hua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/27
CVD
cardiovascular disease
SIRT1
sirtuin1
LV
left ventricular
Sir2
silent information regulator 2
rDNA
recombinant DNA
PI3K
phosphoinositide 3-hydroxykinase
NF-κB
nuclear factor kappa B
FOXOs
forkhead box O transcription factors
ROS
reactive oxygen species
mTOR
mammalian (or mechanistic) target of rapamycin
H2O2
hydrogen peroxide
NO
nitric oxide
GADD45
DNA damage-inducible protein 45
MnSOD
manganese superoxide dismutase
H2S
hydrogen sulfide
HUVECs
human umbilical vein endothelial cells
eNOS
endothelial nitric oxide synthase
miR
microRNA
CR
caloric restriction
AP-1
activator protein 1
STACs
small molecule activators of SIRT1
mTORC1
mTOR complex 1
mTORC2
mTOR complex 2
LC
light chain
IGF
insulin-like growth factor
Atgs
autophagy-related genes
SIRT1
Cardiovascular aging
Oxidative stress
Inflammation
Autophagy
Anti-aging strategies
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