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科研机构
中国医学科学院 北京... [2]
南华大学 [1]
西安交通大学 [1]
暨南大学 [1]
内容类型
期刊论文 [5]
发表日期
2018 [1]
2017 [1]
2016 [1]
2015 [2]
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Co-stimulation of LPAR(1) and S1PR(1/3) increases the transplantation efficacy of human mesenchymal stem cells in drug-induced and alcoholic liver diseases
期刊论文
2018, 卷号: 9
作者:
Li, Mianhuan[1,2]
;
Lv, Yi[1]
;
Chen, Feng[2]
;
Wang, Xiaoyan[1]
;
Zhu, Jiang[3]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/17
Identification of cytochrome P450 isoforms involved in the metabolism of Syl930, a selective S1PR(1) agonist acting as a potential therapeutic agent for autoimmune encephalitis
期刊论文
2017, 卷号: 32, 期号: 1, 页码: 53-60
作者:
Mi, Jiaqi
;
Zhao, Manman
;
Yang, Shu
;
Jia, Yufei
;
Wang, Yan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/04
Syl930
Hydroxylated metabolites
CYP450 isoforms
Metabolism
LC-MS/MS
Pharmacokinetics of H002, a novel S1PR(1) modulator, and its metabolites in rat blood using liquid chromatography-tandem mass spectrometry
期刊论文
2016, 卷号: 6, 期号: 6, 页码: 576-583
作者:
Mi, Jiaqi
;
Zhao, Manman
;
Yang, Shu
;
Yang, Shuang
;
Jin, Jing
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
S1P receptor
S1PR(1) modulator-1-phosphate
SIP analogue
Metabolite
LC-MS/MS
Phamiacokinetics
Periphery blood lymphocyte
Sphingosine kinase 1 as an anticancer therapeutic target
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2015, 卷号: 9, 期号: [db:dc_citation_issue]
作者:
Gao, Ying
;
Gao, Fei
;
Chen, Kan
;
Tian, Mei-li
;
Zhao, Dong-li
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/02
cancer
S1P
S1PR
inhibitors
therapy
sphingosine kinase 1
Apolipoprotein M
期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2015, 卷号: 446, 页码: 21-29
作者:
Ren, Kun
;
Tang, Zhen-Li
;
Jiang, Yue
;
Tan, Yan-Mei
;
Yi, Guang-Hui*
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/27
apo
apolipoprotein
HDL
high-density lipoprotein
HNF-1α,4α
hepatocyte nuclear factor-1α,4α
LRH-1
liver receptor homolog-1
Foxa2
forkhead box A2
PAF
platelet activating factor
LXR
liver X receptor
RXR
retinoid X receptor
FXR
farnesoid X receptor
SHP
small heterodimer partner
S1P
Sphingosine-1-Phosphate
CVD
cardiovascular disease
HDL-C
HDL cholesterol
RCT
reverse cholesterol transport
MHC
major histocompatibility complex class III
TNF
tumor necrosis factor
HRP
haptoglobin-related protein
PON-I
paraoxonase-1
SNP
single nucleotide polymorphism
T1,2D
type 1,2 diabetes
RA
rheumatoid arthritis
ABCA1
ATP-binding cassette transporter A1
PPAR-γ
peroxisome proliferator-activated receptor γ
IL
interleukin
ABCG
ATP-binding cassette sub-family G
CETP
cholesteryl ester transfer protein
SR-B1
scavenger receptor class B member 1
MODY3
maturity-onset diabetes of the young type 3
MUP
major urinary protein
RBP
retinol binding protein
RAR
retinoic acid receptor
TR
thyroid hormone receptor
PI3K
phosphatidylinositol 3-kinase
DHC
dihydrocapsaicin
HRE
hormone response element
IGF-1
insulin-like growth factors
PAF-R
platelet activating factor receptor
TGF-α,β
transforming growth factor-α,β
EGF
epidermal growth factor
HGF
hepatic growth factor
VLDL
very low-density lipoprotein
LDL
low-density lipoprotein
ldlr
LDL receptor
ldlr−/−
LDL-receptor deficient
LCAT
lecithin-cholesterol acyltransferase
CE
cholesteryl ester
TC
total cholesterol
LDL-C
LDL cholesterol
VLDL-C
VLDL cholesterol
CHD
coronary heart disease
Mets
metabolic syndrome
S1PR
S1P receptor
NF-κB
nuclear factor-κB
NO
nitrogen oxide
eNOS
endothelial nitric oxide synthase
apoM-TgN mice
mice overexpressing human apoM by approximately two-fold
apoM-TgH mice
mice overexpressing human apoM by approximately ten-fold
apoM−/− mice
apoM-null mice
apoE−/−
apoE-null mice
Apolipoprotein M
Regulation
Function
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