CORC

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CORC

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2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant 期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:  Hu, Xianglong;  Xun, Qiuju;  Zhang, Tao;  Zhu, Su-Jie;  Li, Qian
收藏  |  浏览/下载：48/0  |  提交时间：2020/07/01
Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR(L858R/T790M/C797S) 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 6, 页码: 869-873
作者:  Li, Qiannan;  Zhang, Tao;  Li, Shiliang;  Tong, Linjiang;  Li, Junyu
收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
EGFR  mutant  inhibitor  C797S  
Revisiting the molecular mechanism of acquired resistance to reversible tyrosine kinase inhibitors caused by EGFR gatekeeper T790M mutation in non-small-cell lung cancer 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2018, 卷号: 27, 期号: 9, 页码: 2160-2170
作者:  Zhao, Yan;  Jiao, Yingjie;  Sun, Fengzhe;  Liu, Xudong
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527
作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang
收藏  |  浏览/下载：57/0  |  提交时间：2019/01/08
Design, synthesis and biological evaluation of novel 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of the epidermal growth factor receptor 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 24, 页码: 7988-7998
作者:  Zhang, Xu;  Peng, Ting;  Ji, Xun;  Li, Jian;  Tong, Linjiang
收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08
Recent developments of small molecule EGFR inhibitors based on the quinazoline core scaffolds 期刊论文
Anti-cancer agents in medicinal chemistry, 2012, 卷号: 12, 期号: 4, 页码: 391-406
作者:  Liu,Y.-J.;  Zhang,C.-M.;  Liu,Z.-P.
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23
AST1306, A Novel Irreversible Inhibitor of the Epidermal Growth Factor Receptor 1 and 2, Exhibits Antitumor Activity Both In Vitro and In Vivo 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 7
作者:  Xie, Hua;  Lin, Liping;  Tong, Linjiang;  Jiang, Yong;  Zheng, Mingyue
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08

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