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科研机构
复旦大学上海医学院 [6]
中南大学 [3]
西安交通大学 [2]
昆明植物研究所 [2]
上海大学 [2]
厦门大学 [1]
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期刊论文 [20]
会议论文 [3]
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2019 [1]
2018 [1]
2017 [1]
2016 [2]
2015 [4]
2014 [2]
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Oncology [1]
物理化学 [1]
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bisdemethoxycurcumin protects against renal fibrosis via activation of fibroblast apoptosis.
期刊论文
European journal of pharmacology, 2019
作者:
Fuquan Jin
;
Ying Jin
;
Jiangxia Du
;
Liyu Jiang
;
Ying Zhang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
Apoptosis
Fibroblasts
Natural
compounds
Renal
fibrosis
bisdemethoxycurcumin
Cytotoxic and renoprotective diterpenoids from Clerodendranthus spicatus
期刊论文
FITOTERAPIA, 2018, 卷号: 125, 页码: 135-140
作者:
Luo, Yong
;
Li, Xiao-Zhen
;
Xiang, Bin
;
Luo, Qi
;
Liu, Jia-Wang
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2018/05/08
Clerodendranthus Spicatus
Diterpenoids
Alkaloid
Cytotoxic Activities
Renal Fibrosis
The loss of Krüppel-like factor 15 in Foxd1+ stromal cells exacerbates kidney fibrosis
期刊论文
Kidney international, 2017, 卷号: 92, 页码: 1178-1193
作者:
Gu Xiangchen[1]
;
Mallipattu Sandeep K[2]
;
Guo Yiqing[3]
;
Revelo Monica P[4]
;
Pace Jesse[5]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/04/26
Krüppel-like factor
Wnt/β-catenin signaling
chronic kidney disease
fibroblasts
fibrosis
Activation of PPAR-gamma inhibits PDGF-induced proliferation of mouse renal fibroblasts
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2016, 卷号: 789, 页码: 222-228
作者:
Lu, Jiamei
;
Shi, Jianhua
;
Gui, Baosong
;
Yao, Ganglian
;
Wang, Li
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/26
Proliferation Peroxisome proliferators activated receptor gamma (PPAR-gamma)
S-phase kinase associated protein-2 (skp2)
Platelet-derived growth factor (PDGF)
Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 卷号: 17, 期号: 2
作者:
Shen, Yang
;
Miao, Naijun
;
Xu, Jinlan
;
Gan, Xinxin
;
Xu, Dan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/06
metformin
renal fibrosis
ERK
angiotensin II
transforming growth factor-
GQ5 Hinders Renal Fibrosis in Obstructive Nephropathy by Selectively Inhibiting TGF-beta-Induced Smad3 Phosphorylation
期刊论文
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2015, 卷号: 26, 期号: 8, 页码: 1827-1838
作者:
Ai, Jun
;
Nie, Jing
;
He, Jiangbo
;
Guo, Qin
;
Li, Mei
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2016/01/19
Activation of AMPK by metformin inhibits TGF-beta-induced collagen production in mouse renal fibroblasts
期刊论文
LIFE SCIENCES, 2015, 卷号: 127, 期号: [db:dc_citation_issue], 页码: 59-65
作者:
Lu, Jiamei
;
Shi, Jianhua
;
Li, Manxiang
;
Gui, Baosong
;
Fu, Rongguo
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/02
Connective tissue growth factor (CTGF)
Transforming growth factor beta 1 (TGF-beta 1)
Renal fibroblasts
Collagen
Adenosine monophosphate-activated protein kinase (AMPK)
Effects of A2BR on the biological behavior of mouse renal fibroblasts during hypoxia
期刊论文
Molecular Medicine Reports, 2015, 卷号: 11, 期号: 6, 页码: 4397-4402
作者:
Tang, Jin
;
Jiang, Xianzhen
;
Zhou, Yihong
;
Dai, Yingbo*
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
hypoxia
fibroblast
adenosine receptor
cytokine
alpha-smooth muscle actin
Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis
期刊论文
The International Journal of Biochemistry & Cell Biology, 2015, 卷号: 67, 页码: 92-100
作者:
Luo, Yangyang
;
Wang, Yong
;
Shu, Ye
;
Lu, Qianjin
;
Xiao, Rong*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
SSc
systemic sclerosis
SRC
scleroderma renal crisis
PAH
pulmonary arterial hypertension
SMR
standardized mortality ratio
DNMTs
DNA methyltransferases
SAM
S-adenosyl-methionine
5mC
5-methylcytosine
MBD
methyl-CpG-binding domain
Tet
ten–eleven translocation
HATs
histone acetyltransferases
HDACs
histone deacetylases
MiRNAs
microRNAs
MZ
monozygotic
DZ
dizygotic
MVECs
microvascular endothelial cells
FBs
fibroblasts
JAMs
junctional adhesion molecules
CTGF
connective tissue growth facto
TGF-β
transforming growth factor beta
CCN2
connective tissue growth factor
Fli1
Friend leukemia integration-1
TF
transcription factor
PECAM
platelet/endothelial cell adhesion molecule
PDGF
platelet derived growth factor
S1P1
sphingosin 1 phosphate
CXCL5
CXC chemokine ligand-5
BMPs
bone morphogenetic proteins
BMPRII
bone morphogenetic protein type II receptor
ET-1
endotheline-1
uPA
urokinase-type plasminogen activator
MBD
methyl-CpG-binding domain protein
ICAM
intercellular adhesion molecule
KLF5
Kruppel-like factor 5
Tregs
regulatory T cells
Runx1
Runt-related transcription factor 1
FOXP3
forkhead box protein 3 gene
ECM
extra cellular matrix
PDGF
platelet-derived growth factor
dSSc
diffuse systemic sclerosis
lSSc
limited systemic sclerosis
PCAF
protein-associated factor
Egr-1
early growth response 1
DDR2
discoidin domain receptor 2
TAB1
TGF-β activated kinase 1 binding protein 1
BAFF
B cell-activating factor
TSP-2
thrombospondin-2
MRTSS
Modified Rodnan total skin score
SDAI
Valentini scleroderma disease activity index
HC
healthy controls
SLE
systemic lupus erythematosus
SSD
scleroderma spectrum disorder
MTX
methylaminopterin
CYC
cyclophosphamide
MMF
mycophenolate mofetil
ACE
angiotensin converting enzyme
NO
nitric oxide
Systemic sclerosis
Epigenetic mechanisms
Biomarker
Therapy
Ergosterol peroxide from Cordyceps cicadae ameliorates TGF-beta 1-induced activation of kidney fibroblasts
期刊论文
PHYTOMEDICINE, 2014, 卷号: 21, 期号: 3, 页码: 372-378
作者:
Zhu, Rong
;
Zheng, Rong
;
Deng, Yueyi
;
Chen, Yiping
;
Zhang, Shuwei
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Ergosterol peroxide
Cordyceps cicadae
TGF-beta 1
Chronic kidney disease
Fibroblast-to-myofibroblast transdifferentiaton
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