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CORC

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The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers 期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:  Tao, Zhonghua;  Liu, Jianxia;  Li, Ting;  Xu, Hong;  Chen, Kai
收藏  |  浏览/下载：33/0  |  提交时间：2022/01/10
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 9, 页码: 19
作者:  Xiong, Zhaoping;  Jeon, Minji;  Allaway, Robert J.;  Kang, Jaewoo;  Park, Donghyeon
收藏  |  浏览/下载：23/0  |  提交时间：2021/11/04
The genomic landscape of young and old lung cancer patients highlights age-dependent mutation frequencies and clinical actionability in young patients 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2021
作者:  Cai, Lei;  Chen, Yong;  Tong, Xiaoling;  Wu, Xue;  Bao, Hua
收藏  |  浏览/下载：65/0  |  提交时间：2021/06/15
Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants 期刊论文
European Journal of Medicinal Chemistry, 2018, 卷号: Vol.143, 页码: 1148-1164
作者:  Yang, J.;  Chen, K.;  Zhang, G.;  Yang, Q.-Y.;  Li, Y.-S.
收藏  |  浏览/下载：4/0  |  提交时间：2019/02/25
Evaluation of in vitro and in vivo activity of a multityrosine kinase inhibitor, AL3810, against human thyroid cancer 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1533-1542
作者:  Xie, Qin;  Chen, Hui;  Ai, Jing;  Gao, Ying-lei;  Geng, Mei-yu
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Design, Synthesis, and Pharmacological Evaluation of Novel Multisubstituted Pyridin-3-amine Derivatives as Multitargeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 14, 页码: 6018-6035
作者:  Zhu, Wei;  Chen, Hui;  Wang, Yulan;  Wang, Jiang;  Peng, Xia
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
Synthesis and structure-activity relationship study of pyrazolo[3,4-d]pyrimidines as tyrosine kinase RET inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2544-2548
作者:  Wang, Chengyan;  Liu, Hongchun;  Song, Zilan;  Ji, Yinchun;  Xing, Li
收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08
Two pairs of rare naturally occurring 4-hydroxy-4-methyl-2,5-heptanedione derivatives from the red alga Chondria crassicaulis 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 卷号: 19, 期号: 6, 页码: 572-580
作者:  Tong, Lin;  Zhang, Yi;  Liu, Ai-Hong;  Yao, Li-Gong;  Guo, Yue-Wei
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Discovery of 4-chloro-3-(5-(pyridin-3-yl)-1,2,4-oxadiazole-3-yl) benzamides as novel RET kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 23, 页码: 5679-5684
作者:  Han, Mei;  Li, Shan;  Ai, Jing;  Sheng, Rong;  Hu, Yongzhou
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08

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