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北京大学 [3]
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中国科学院大学 [2]
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期刊论文 [21]
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Trim27 mediates stat3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis
期刊论文
Nature communications, 2018, 卷号: 9, 页码: 16
作者:
Zhang, Hong-Xia
;
Xu, Zhi-Sheng
;
Lin, Hen
;
Li, Mi
;
Xia, Tian
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/05/08
Design, Synthesis, and Pharmacological Evaluation of Novel Multisubstituted Pyridin-3-amine Derivatives as Multitargeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 14, 页码: 6018-6035
作者:
Zhu, Wei
;
Chen, Hui
;
Wang, Yulan
;
Wang, Jiang
;
Peng, Xia
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Synthesis and Activity Evaluation of Novel 3,4-Dihydro-benzo[b]-oxazepin-5(2H)-one Derivatives as Protein Kinases Inhibitors
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 6, 页码: 1463-1472
作者:
Hou Guige
;
Jiang Chengshi
;
Liu Hongchun
;
Tong Linjiang
;
Peng Xia
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
3,4-dihydro-benzo[b]oxazepin-5(2H)-one derivatives
synthesis
protein-tyrosine kinases inhibitors
ErbB1
ErbB2
The ubiquitin ligase trim27 functions as a host restriction factor antagonized by mycobacterium tuberculosis ptpa during mycobacterial infection
期刊论文
Scientific reports, 2016, 卷号: 6, 页码: 13
作者:
Wang, Jing
;
Teng, Jade L. L.
;
Zhao, Dongdong
;
Ge, Pupu
;
Li, Bingxi
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  |  
浏览/下载:28/0
  |  
提交时间:2019/05/09
Identification of tra2b-dnah5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma
期刊论文
Cell research, 2016, 卷号: 26, 期号: 10, 页码: 1149-1164
作者:
Li, Fei
;
Fang, Zhaoyuan
;
Zhang, Jian
;
Li, Chen
;
Liu, Hongyan
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/05/09
Lung squamous cell carcinoma
Molecular targeted therapy
Exon array analyses
Tra2b-dnah5 fusion
Selumetinib
Identification of a Vav2-dependent mechanism for GDNF/Ret control of mesolimbic DAT trafficking
期刊论文
NATURE NEUROSCIENCE, 2015, 卷号: 18, 期号: 8, 页码: 1084-1084
作者:
Zhu, SY
;
Zhao, CJ
;
Wu, YY
;
Yang, QQ
;
Shao, AY
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2015/12/30
DOPAMINE TRANSPORTER TRAFFICKING
NUCLEOTIDE EXCHANGE FACTORS
VAV FAMILY
PLASMA-MEMBRANE
KINASE
MICE
PHOSPHORYLATION
RECEPTOR
NEURONS
GROWTH
Immunohistochemical Detection of RET Proto-oncogene Product in Tumoral and Nontumoral Mucosae of Gastric Cancer
期刊论文
ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY, 2014, 卷号: 36, 期号: 3
作者:
Zhang, Fan
;
Tang, Jian Min
;
Wang, Li
;
Wu, Ping Ping
;
Zhang, Mei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
EGFR
epidermal growth factor receptor
gastric mucosa
oncogenesis
RET protein
stomach neoplasm
The Conformation of Substrate and Oligomeric State of DegP Regulate Its Chaperone and Protease Function
其他
2014-01-01
Xin Sheng Zhao
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2017/12/03
Protein quality control
Protease
Molecular chaperone
smF RET
Protein quality control
Protease
Molecular chaperone
smF RET
Isolation and characterization of tumor necrosis factor receptor-associated factor 6 (TRAF6) from grouper, Epinephelus tauvina
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2014, 卷号: 39, 期号: 1, 页码: 61-68
Wei, JG
;
Guo, ML
;
Gao, P
;
Ji, HS
;
Li, PF
;
Yan, Y
;
Qin, QW
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2014/12/11
Epinephelus tauvina
TRAF6
SGIV
GNNV
Intracellular localization
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