CORC

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CORC

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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo 期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:  Sun, Hao;  Bai, Xiaoyi;  Zhang, Yiting;  Gao, Yanan;  Dai, Jiajia
收藏  |  浏览/下载：10/0  |  提交时间：2024/06/04
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
收藏  |  浏览/下载：12/0  |  提交时间：2024/04/07
Targeting KRAS mutant cancers: from druggable therapy to drug resistance 期刊论文
MOLECULAR CANCER, 2022, 卷号: 21
作者:  Zhu, Chunxiao;  Guan, Xiaoqing;  Zhang, Xinuo;  Luan, Xin;  Song, Zhengbo
收藏  |  浏览/下载：31/0  |  提交时间：2022/12/23
Cardiotoxicity of Epidermal Growth Factor Receptor 2-Targeted Drugs for Breast Cancer 期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12
作者:  Yang, ZiYan;  Wang, Wei;  Wang, Xiaojia;  Qin, ZhiQuan
收藏  |  浏览/下载：43/0  |  提交时间：2022/01/10
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 213, 页码: 17
作者:  Xiao, Xuanzheng;  Lai, Mengzhen;  Song, Zilan;  Geng, Meiyu;  Ding, Jian
收藏  |  浏览/下载：49/0  |  提交时间：2021/05/24
PD-L1 expression levels on tumor cells affect their immunosuppressive activity 期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 5, 页码: 5399-5407
作者:  Zheng, Yang;  Fang, You-Chen;  Li, Jing
收藏  |  浏览/下载：55/0  |  提交时间：2020/07/01
Fragment-based drug discovery of triazole inhibitors to block PDE delta-RAS protein-protein interaction 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163, 页码: 597-609
作者:  Chen, Danqi;  Chen, Yuehong;  Lian, Fulin;  Chen, Liu;  Li, Yanlian
收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 597-609
作者:  Chen, Danqi;  Chen, Yuehong;  Lian, Fulin;  Chen, Liu;  Li, Yanlian
收藏  |  浏览/下载：92/0  |  提交时间：2019/01/08
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562
作者:  Liu, Feifei;  Yang, Xiaotong;  Geng, Meiyu;  Huang, Min
收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08
Potential anti-tumor mechanisms of renin angiotensin system inhibitors through inhibiting angiogenesis and influencing angiotensin II actions 期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 卷号: 11, 期号: 10
作者:  Zhao, Bei;  Sun, Hong;  Zhang, Xiao-Dan;  Li, Guang-Hui;  Zhao, Yong-Hong
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05

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