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上海药物研究所 [26]
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Palladium-Catalyzed Selective Synthesis of Dibenzo[c,e]azepin-5-ols and Benzo[c]pyrido[2,3-e]azepin-5-ols
期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2019, 页码: 8
作者:
Yao, Xinrong
;
Shao, Yinlin
;
Hu, Maolin
;
Zhang, Maosheng
;
Li, Shaotong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
palladium-catalyzed
tandem reaction
dibenzo[c
e]azepin-5-ols
benzo[c]pyrido[2
3-e]azepin-5-ols
nitriles
Stereoselective Synthesis of Pyrido- and Pyrrolo[1,2-c][1,3]oxazin-1-ones via a Nucleophilic Addition Cyclization Process of N,O-Acetal with Ynamides
期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 84, 期号: 2
作者:
Han, Pan
;
Mao, Zhuo-Ya
;
Si, Chang-Mei
;
Zhou, Zhu
;
Wei, Bang-Guo
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrido[4,3-c]azepin-5-one-based novel chemotype CCR2 antagonists via scaffold hopping strategy
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3559-3572
作者:
Qin, Li-Huai
;
Wang, Zhi-Long
;
Xie, Xin
;
Long, Ya-Qiu
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
6,7,8,9-Tetrahydro-5H-pyrido[43-c]azepin-5-one
3,4-Dihydro-2,6-naphthyridin-1(2H)-one
CCR2 antagonist
Scaffold hopping
Structure-activity relationship
Selectivity of CCR2 over CCR5
Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK)
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:
Gu, Zhanni
;
Wu, Lingyan
;
Duan, Yanan
;
Wang, Jiang
;
Zhou, Shengbin
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
Adenosine 5 '-monophosphate-activated protein kinase
AMPK activators
Berberine
Tetrahydroberberine
T2DM
Side-chain fluorination on the pyrido[3,4-b]pyrazine unit towards efficient photovoltaic polymers
期刊论文
SCIENCE CHINA-CHEMISTRY, 2018, 卷号: 61, 期号: 2, 页码: 206-214
作者:
Wang, Tao
;
Feng, Liuliu
;
Yuan, Jun
;
Jiang, Lihui
;
Deng, Wei
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/04/09
Side-chain Fluorination
Efficient Photovoltaics
Pyrido[3
4-b]Pyrazine
Oral administration of indole substituted dipyrido[2,3-d]pyrimidine derivative exhibits anti-tumor activity via inhibiting AKT and ERK1/2 on hepatocellular carcinoma.
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018
作者:
Yao, Hong
;
Yan, Hongru
;
Gao, Xiaoge
;
Zhu, Songlei
;
Cen, Lanqi
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  |  
浏览/下载:16/0
  |  
提交时间:2019/01/31
Metal-Free [3+2] Tandem Cyclization Synthesis of Unique 11H-Pyrido[3,2:4,5]Pyrrolo[3,2-b]Indolizine from 7-Azaindoles and Pyridotriazoles
期刊论文
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2018, 期号: 30, 页码: 4197-4201
作者:
Zhang, GT (Zhang, Guo-Tai)[ 1 ]
;
Zhang, J (Zhang, Jing)[ 1 ]
;
Xu, YJ (Xu, Yan-Jun)[ 2 ]
;
Dong, L (Dong, Lin)[ 1 ]
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2018/09/18
Metal-free
Carbene Insertion
Nitrogen Heterocycles
Polycycles
Synthetic Methods
A simple fluorescent probe for monitoring pH in cellsbased on new fluorophorepyrido[1,2-a]benzimidazole
期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2018, 卷号: 254
作者:
Ge, Yanqing
;
Wei, Peng
;
Wang, Teng
;
Cao, Xiaoqun
;
Zhang, Dongsheng
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
pyrido[1,2-a]benzimidazole
Fluorescent probe
ICT
Bioimaging
Visible-Light-Induced Trifluoromethylation of Isonitrile-Substituted Indole Derivatives: Access to 1-(Trifluoromethyl)-4,9-dihydro-3H-pyrido[3,4-b]indole and beta-Carboline Derivatives
期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2018, 卷号: 360, 期号: 15
作者:
Liu, Jiaxin
;
Li, Longhai
;
Yu, Liuzhu
;
Tang, Lisha
;
Chen, Qin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
visible-light catalyst
trifluoromethylation
beta-carboline derivatives
Togni II reagent
biological study
Synthesis and biological evaluation of irreversible EGFR tyrosine kinase inhibitors containing pyrido[3,4-d]pyrimidine scaffold
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 页码: 3619-3633
作者:
Zhang, Hao
;
Wang, Jin
;
Zhao, Hong-Yi
;
Yang, Xue-Yan
;
Lei, Hao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/11/26
Pyrido[3,4-d]pyrimidine
Anticancer
Drug design
Irreversible inhibitors
EGFR-TKIs
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