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Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng
收藏  |  浏览/下载:24/0  |  提交时间:2022/12/23
Supramolecular Antagonists Promote Mitochondrial Dysfunction 期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 13, 页码: 5730-5737
作者:  Li, Mingming;  Song, Yanqiu;  Song, Na;  Wu, Guangyao;  Zhou, Hao
收藏  |  浏览/下载:91/0  |  提交时间:2021/08/17
Molecular dynamics simulation revealed the intrinsic conformational change of cellular inhibitor of apoptosis protein-1 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020, 卷号: 38, 期号: 4, 页码: 975-984
作者:  Xu, Heng;  Tang, Zhengkuan;  Zuo, Yu;  Xiong, Fengmin;  Chen, Kaixian
收藏  |  浏览/下载:47/0  |  提交时间:2020/07/01
Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 8
作者:  Chen, Shuanghong;  Lu, Mengjie;  Liu, Dongsheng;  Yang, Lingyun;  Yi, Cuiying
收藏  |  浏览/下载:16/0  |  提交时间:2020/07/01
Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling. 期刊论文
Evidence-based Complementary & Alternative Medicine, 2019, 页码: 1-11
作者:  Guo, Yubo;  Pei, Xiaohua
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/17
Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes 期刊论文
BRAIN, 2018, 卷号: 141, 页码: 1782-1798
作者:  Song, Haikun;  Li, Hexuan;  Guo, Shimeng;  Pan, Yuyin;  Fu, Yuhua
收藏  |  浏览/下载:52/0  |  提交时间:2019/01/08
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist 期刊论文
CELL DISCOVERY, 2018, 卷号: 4
作者:  Yin, Wanchao;  Zhou, X. Edward;  Yang, Dehua;  de Waal, Parker W.;  Wang, Meitian
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 2, 页码: 443-454
作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Tan, Wenfu;  Zhang, Ao
收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses 期刊论文
JOURNAL OF NEUROSCIENCE, 2017
Lee, Sung-Jin; Wei, Mengping; Zhang, Chen; Maxeiner, Stephan; Pak, ChangHui; Botelho, Salome Calado; Trotter, Justin; Sterky, Fredrik H.; Sudhof, Thomas C.
收藏  |  浏览/下载:6/0  |  提交时间:2017/12/03
The sphingosine-1-phosphate analogue, FTY-720, promotes the proliferation of embryonic neural stem cells, enhances hippocampal neurogenesis and learning and memory abilities in adult mice 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2016, 卷号: 173, 期号: 18, 页码: 2793-2807
作者:  Sun, Yili;  Hong, Feng;  Zhang, Lei;  Feng, Linyin
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08


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