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上海药物研究所 [49]
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Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:
Liang, Xiaofei
;
Wang, Chun
;
Wang, Beilei
;
Liu, Juan
;
Qi, Shuang
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/12/23
CSF1R inhibitor
Kinase inhibitor
Macrophage polarization
New and effective EGFR-targeted fluorescence imaging technology for intraoperative rapid determination of lung cancer in freshly isolated tissue
期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022, 页码: 14
作者:
Li, Changjian
;
Mi, Jiahui
;
Wang, Yueqi
;
Zhang, Zeyu
;
Guo, Xiaoyong
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/11/14
Intraoperative imaging technology
Lung cancer
Fluorescence-labeled antibody probe
Epidermal growth factor receptor
Surgical tumor resection
Carbonic anhydrase IX stratifies patient prognosis and identifies nodal status in animal models of nasopharyngeal carcinoma using a targeted imaging strategy
期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022, 页码: 13
作者:
Huang, Wenhui
;
Wang, Kun
;
Huang, Weiyuan
;
He, Zicong
;
Zhang, Jingming
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2022/09/19
Carbonic anhydrase IX
Nasopharyngeal carcinoma
Extranodal extension
Occult lymph node metastasis
Ultrasonography-guided spectroscopic photoacoustic imaging
Effects of Pyropia yezoensis eYnzymatic hydrolysate on the growth and immune regulation of the zebrafish
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2022, 卷号: 122, 页码: 21-28
作者:
Wang, Xiaoqing
;
Liu, Jing
;
Geng, Lihua
;
Yang, Yue
;
Wu, Ning
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/08/17
Pyropia yezoensis
Immune regulation
Growth promotion
Zebrafish
Intestinal flora
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Jiang-yan
;
Qi, Shuang
;
Wu, Hong
;
Wang, Ao-li
;
Liu, Qing-wang
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2022/03/28
HER2
breast cancers
gastric cancers
irreversible inhibitor
drug resistance
Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2021, 页码: 14
作者:
Duan, Nianxiu
;
Li, Junjun
;
Song, Sha
;
Wang, Feng
;
Yang, Yiwei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
drug delivery
pancreatic cancer
prodrugs
smart liposomes
tumor-specific vascular promotion
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
;
Peng, Xia
;
Zhan, Zhengsheng
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/08/17
Axl
Cancer
Inhibitor
Pyrrolo[2,3-d]pyrimidine
Stimuli-Sheddable Nanomedicine Overcoming Pathophysiological Barriers for Potentiating Immunotherapy of Cancer
期刊论文
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2021, 卷号: 17, 期号: 8, 页码: 1486-1509
作者:
Wang, Jiaxin
;
Zhou, Mengxue
;
Chen, Fangmin
;
Liu, Xiao
;
Gao, Jin
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/11/04
Cancer Immunotherapy
Tumor Microenvironment
Stimuli-Responsiveness
Sheddable Nanoparticles
Pathophysiological Barriers
Nanocrystal-loaded liposome for targeted delivery of poorly water-soluble antitumor drugs with high drug loading and stability towards efficient cancer therapy
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 599
作者:
Liang, Huamin
;
Zou, Fengming
;
Liu, Qingwang
;
Wang, Beilei
;
Fu, Liyi
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/05/17
Liposome
Drug nanocrystal
Core-shell
Drug delivery
Tumor therapy
BCR-ABL
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
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