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上海药物研究所 [27]
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中国医学科学院 北京... [9]
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中国水产科学院 [3]
上海中医药大学 [3]
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期刊论文 [55]
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Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
Design, Synthesis, and Biological Evaluation of Novel Pyrimido[4,5-b]indole Derivatives Against Gram-Negative Multidrug-Resistant Pathogens
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8644-8665
作者:
Kong, Qidi
;
Pan, Wei
;
Xu, Heng
;
Xue, Yaru
;
Guo, Bin
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/08/17
Graph neural networks for automated de novo drug design
期刊论文
DRUG DISCOVERY TODAY, 2021, 卷号: 26, 期号: 6, 页码: 1382-1393
作者:
Xiong, Jiacheng
;
Xiong, Zhaoping
;
Chen, Kaixian
;
Jiang, Hualiang
;
Zheng, Mingyue
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  |  
浏览/下载:20/0
  |  
提交时间:2021/08/17
Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 2, 页码: 396-409
作者:
Zhang, Yi-fan
;
Liu, Yan-mei
;
Yu, Chen
;
Wang, Ya-ting
;
Zhan, Yan
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  |  
浏览/下载:69/0
  |  
提交时间:2021/05/24
diabetes
henagliflozin
pharmacodynamics
pharmacokinetics
SGLT-2 inhibitors
Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China
期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 1, 页码: 5-23
作者:
Yu, Xuan
;
Chu, Zixuan
;
Li, Jian
;
He, Rongrong
;
Wang, Yaya
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  |  
浏览/下载:69/0
  |  
提交时间:2021/05/24
Pharmacokinetics
drug-drug interaction
antibiotic
sepsis
transporter
enzyme
Discovery of a highly selective VEGFR2 kinase inhibitor CHMFL-VEGFR2-002 as a novel anti-angiogenesis agent
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10
作者:
Jiang, Zongru
;
Wang, Li
;
Liu, Xuesong
;
Chen, Cheng
;
Wang, Beilei
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  |  
浏览/下载:28/0
  |  
提交时间:2020/11/26
Cancer
VEGFR2 kinase
Kinase inhibitor
Angiogenesis
Inhibitor selectivity
Current trends in drug metabolism and pharmacokinetics
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1113-1144
作者:
Li, Yuhua
;
Meng, Qiang
;
Yang, Mengbi
;
Liu, Dongyang
;
Hou, Xiangyu
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  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
Pharmacokinetics
Drug metabolism
Drug-drug interactions
Modeling
Metabolizing enzymes
Transporters
Nuclear receptors
Noncoding RNAs
Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 175, 页码: 11
作者:
Gao, Yuxiong
;
Zhang, Dan
;
Yang, Changyong
;
Duan, Xiaotao
;
Li, Xiuli
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Anti-CD47 monoclonal antibody
LC-MS
Adsorption issue
Electrochemiluminescence
Pharmacokinetics
Cross-validation
Pharmacokinetics-pharmacodynamics and tissue distribution analysis of Low Polar extract of Xiaoyao Powder combined with rat model of chronic unpredictable mild stress
期刊论文
2019, 卷号: 42, 期号: 7-8, 页码: 173-183
作者:
Gao, Xiaoxia
;
Wang, Peng
;
Wu, Li
;
Liu, Jiali
;
Fang, Yuan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Pharmacokinetics-pharmacodynamics (PK-PD)
low polar extract of Xiaoyao powder (XYP-A)
polyacetylene
Chronic Unpredictable Mild Stress (CUMS)
monoamine neurotransmitters
Effect of temperature on plasma and tissue kinetics of doxycycline in grass carp (Ctenopharyngodon idella) after oral administration
期刊论文
AQUACULTURE, 2019, 卷号: 511
作者:
Xu, Ning[1]
;
Li, Miao[2]
;
Fu, Yu[3]
;
Zhang, Xiaomei[4]
;
Dong, Jing[5]
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/01/02
Temperature
Pharmacokinetics
Doxycycline
Grass carp
Tissue residue
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