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New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Yong-Mei;  Ye, Lu-Yu;  Li, Tian-Yu;  Guo, Fan;  Guo, Fei
收藏  |  浏览/下载:20/0  |  提交时间:2022/01/04
Different conformational responses of the beta(2)-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8
作者:  Yang, Fan;  Ling, Shenglong;  Zhou, Yingxin;  Zhang, Yanan;  Lv, Pei
收藏  |  浏览/下载:43/0  |  提交时间:2021/11/01
Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor 期刊论文
ELIFE, 2021, 卷号: 10, 页码: 20
作者:  Zhao, Fenghui;  Zhang, Chao;  Zhou, Qingtong;  Hang, Kaini;  Zou, Xinyu
收藏  |  浏览/下载:36/0  |  提交时间:2021/08/17
TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia 期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 378, 期号: 1, 页码: 20-30
作者:  Wang, Yu;  He, Yang;  Yang, Feipu;  Abame, Melkamu Alemu;  Wu, Chunhui
收藏  |  浏览/下载:37/0  |  提交时间:2021/11/04
Insights into the molecular mechanism of positive cooperativity between partial agonist MK-8666 and full allosteric agonist AP8 of hGPR40 by Gaussian accelerated molecular dynamics (GaMD) simulations 期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 页码: 3978-3989
作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Liu, Huanxiang;  Yao, Xiaojun
收藏  |  浏览/下载:12/0  |  提交时间:2021/12/08
Characterization of the GABAergic system in Asian clam Corbicula fluminea: Phylogenetic analysis, tissue distribution, and response to the aquatic contaminant carbamazepine 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2021, 卷号: 239
作者:  Chen, Huihui;  Gu, Xiaohong;  Zeng, Qingfei;  Mao, Zhigang;  Martyniuk, Christopher J.
收藏  |  浏览/下载:26/0  |  提交时间:2022/03/10
One-day tropisetron treatment improves cognitive deficits and P50 inhibition deficits in schizophrenia 期刊论文
NEUROPSYCHOPHARMACOLOGY, 2020, 卷号: 45, 期号: 8, 页码: 1362-1368
作者:  Xia, Luyao;  Liu, Lei;  Hong, Xiaohong;  Wang, Dongmei;  Wei, Gaoxia
收藏  |  浏览/下载:28/0  |  提交时间:2020/06/08
Synthesis and biological investigation of triazolopyridinone derivatives as potential multireceptor atypical antipsychotics 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 8, 页码: 6
作者:  Shi, Wenqiang;  Wang, Yu;  Wu, Chunhui;  Yang, Feipu;  Zheng, Wei
收藏  |  浏览/下载:25/0  |  提交时间:2020/07/01
Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery 期刊论文
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 8, 页码: 2260-2268
作者:  Jiang, Haowen;  Zhou, X. Edward;  Shi, Jingjing;  Zhou, Zhi;  Zhao, Guanguan
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/01
3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 18, 页码: 8136-8154
作者:  Baqi, Younis;  Pillaiyar, Thanigaimalai;  Abdelrahman, Aliaa;  Kaufmann, Olesja;  Aishaibani, Samer
收藏  |  浏览/下载:105/0  |  提交时间:2019/01/08


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