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CORC

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Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载：41/0  |  提交时间：2022/01/04
The genomic landscape of young and old lung cancer patients highlights age-dependent mutation frequencies and clinical actionability in young patients 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2021
作者:  Cai, Lei;  Chen, Yong;  Tong, Xiaoling;  Wu, Xue;  Bao, Hua
收藏  |  浏览/下载：64/0  |  提交时间：2021/06/15
Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic PIK3CA(H1047R) accompanied with pro-tumorigenic secretome 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 3, 页码: 817-829
作者:  Liu, Xue-Ling;  Liu, Jia-Li;  Xu, Yi-Chao;  Zhang, Xi;  Wang, Yu-Xiang
收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01
The distinct clinicopathological and prognostic implications of PIK3CA mutations in breast cancer patients from Central China 期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 1473-1492
作者:  Lin, Wenchu;  Wu, Haibo;  Wang, Wei;  Du, Jun;  Li, Hong
收藏  |  浏览/下载：49/0  |  提交时间：2019/06/20
The distinct clinicopathological and prognostic implications of pik3ca mutations in breast cancer patients from central china 期刊论文
Cancer management and research, 2019, 卷号: 11, 页码: 1473-1492
作者:  Wu, Haibo;  Wang, Wei;  Du, Jun;  Li, Hong;  Wang, Huogang
收藏  |  浏览/下载：60/0  |  提交时间：2019/05/08
The distinct clinicopathological and prognostic implications of PIK3CA mutations in breast cancer patients from Central China 期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 期号: 无, 页码: 1473-1492
作者:  Wu, Haibo;  Wang, Wei;  Du, Jun;  Li, Hong;  Wang, Huogang
收藏  |  浏览/下载：4/0  |  提交时间：2020/05/21
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:  Wang, Jia;  Gong, Grace Qun;  Zhou, Yan;  Lee, Woo-Jeong;  Buchanan, Christina Maree
收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia
收藏  |  浏览/下载：88/0  |  提交时间：2019/01/08
Prediction of the combined effects of multiple estrogenic chemicals on MCF-7 human breast cancer cells and a preliminary molecular exploration of the estrogenic proliferative effects and related gene expression 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 卷号: 160, 页码: 1-9
作者:  Wang, Zijian;  Rao, Kaifeng;  Ma, Mei;  Ji, Xiaoya;  Huang, Chao
收藏  |  浏览/下载：41/0  |  提交时间：2019/06/24
The genemutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing 期刊论文
2018, 卷号: 144, 期号: 11, 页码: 2149-2159
作者:  Zou, Shuang-Mei;  Li, Wei-Hua;  Wang, Wen-Miao;  Li, Wen-Bin;  Shi, Su-Sheng
收藏  |  浏览/下载：5/0  |  提交时间：2020/01/03

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