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上海药物研究所 [91]
山东大学 [12]
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Machine learning model for predicting physical activity related bleeding risk in Chinese boys with haemophilia A
期刊论文
THROMBOSIS RESEARCH, 2023, 卷号: 232, 页码: 43-53
作者:
Ai, Di
;
Cui, Chang
;
Tang, Yongqiang
;
Wang, Yan
;
Zhang, Ningning
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/26
Haemophilia
Children
Machine learning
Bleeding predictive modelling
Physical activity
Optimization of ODAP-Urea-based dual-modality PSMA targeting probes for sequential PET-CT and optical imaging
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 10
作者:
Li, Yuan
;
Duan, Xiaojiang
;
Xu, Hongchuang
;
Zhang, Jingming
;
Zhou, Haoxi
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/07/25
Prostate cancer
Prostate-specific membrane antigen (PSMA)
Dual-modality imaging
PET imaging
Optical imaging
Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:
Qu, Bingxue
;
Xu, Yongjin
;
Lu, Yang
;
Zhuang, Weihao
;
Jin, Xinxin
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/12/23
XPO1
Multiple myeloma
MM.1S
N-phenylsulfonamide
Oral administration
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
;
Peng, Xia
;
Zhan, Zhengsheng
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  |  
浏览/下载:47/0
  |  
提交时间:2021/08/17
Axl
Cancer
Inhibitor
Pyrrolo[2,3-d]pyrimidine
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Wu, Ya-li
;
Xue, Ya-ru
;
Guo, Zi-tao
;
Chen, Zhen-dong
;
Ge, Xin-yu
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
furmonertinib (alflutinib
AST2818)
quantitative proteomics
sandwich-cultured human hepatocytes
Bruton's tyrosine kinase inhibitors in primary central nervous system lymphoma-evaluation of anti-tumor efficacy and brain distribution
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2021, 卷号: 10
作者:
Yu, Haifeng
;
Kong, Haiying
;
Li, Cong
;
Dong, Xiaowu
;
Wu, Yizhe
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  |  
浏览/下载:24/0
  |  
提交时间:2021/08/31
Primary central nervous system lymphoma ( PCNSL)
Bruton's tyrosine kinase (BTK)
ibrutinib
zanubrutinib
tirabrutinib
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:
Zhou, Yu
;
Li, Xiaoguang
;
Chen, Kerong
;
Ba, Qian
;
Zhang, Xu
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/06/11
Structural optimization
Lead compound
Artemisinin derivatives
Cancer
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:
Zhou, Yu
;
Li, Xiaoguang
;
Chen, Kerong
;
Ba, Qian
;
Zhang, Xu
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/05/24
Structural optimization
Lead compound
Artemisinin derivatives
Cancer
High nitrogen stainless steel drug-eluting stent - Assessment of pharmacokinetics and preclinical safety in vivo
期刊论文
BIOACTIVE MATERIALS, 2020, 卷号: 5, 期号: 4, 页码: 779-786
作者:
Chen, Shanshan
;
Yao, Zhifeng
;
Guan, Yongbiao
;
Yang, Hui
;
Shahzad, M. Babar
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/02/02
Sirolimus-eluting stent
Pharmacokinetics
Preclinical safety
Tissue response
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