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CORC

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Facile and Cost-Effective Route for the Synthesis of Simmerafil 期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2432-2437
作者:  Odilov, Abdullajon;  Liu, Yin;  Hu, Tianwen;  Jiang, Xiangrui;  Suo, Jin
收藏  |  浏览/下载：20/0  |  提交时间：2022/01/18
A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959
作者:  Qian, Hongjie;  Chen, Qian;  Lang, Liyu;  Zou, Yang;  Pu, Huahua
收藏  |  浏览/下载：35/0  |  提交时间：2021/08/17
艾拉片对重复束缚应激所致勃起功能障碍小鼠的治疗作用（英文） 期刊论文
Journal of Chinese Pharmaceutical Sciences, 2021, 卷号: 30, 期号: 11, 页码: 883-894
作者:  高泽宇1,2;  陈君3,4;  阿依努尔·热合曼3,4,5;  孙懿1,2;  吴涛3
收藏  |  浏览/下载：19/0  |  提交时间：2022/01/25
Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 191, 页码: 8
作者:  Zhang, Mengqi;  Liu, Haiming;  He, Jiajin;  Gui, Yuzhou;  Qian, Hongjie
收藏  |  浏览/下载：30/0  |  提交时间：2020/12/24
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Tian, Qian-qian;  Zhu, Yun-ting;  Diao, Xing-xing;  Zhang, Xiang-lei;  Xu, Ye-chun
收藏  |  浏览/下载：69/0  |  提交时间：2020/12/24
Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:  Pan, Lulu;  Guo, Shuang;  Chen, Xiaoyan;  Jiang, Xiangrui;  Shen, Jingshan
收藏  |  浏览/下载：55/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01
Gold-catalyzed Rapid Construction of Nitrogen-containing Heterocyclic Compound Library with Scaffold Diversity and Molecular Complexity 期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2019, 卷号: 361, 期号: 6, 页码: 1419-1440
作者:  Qiao, Jin;  Jia, Xiuwen;  Li, Pinyi;  Liu, Xiaoyan;  Zhao, Jingwei
收藏  |  浏览/下载：6/0  |  提交时间：2020/07/01
Green and Facile Assembly of Diverse Fused N-Heterocycles Using Gold-Catalyzed Cascade Reactions in Water 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 5, 页码: 30
作者:  Jia, Xiuwen;  Li, Pinyi;  Liu, Xiaoyan;  Lin, Jiafu;  Chu, Yiwen
收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载：137/0  |  提交时间：2019/06/28

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