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浏览/检索结果: 共4条，第1-4条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030 作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li 收藏  |  浏览/下载：114/0  |  提交时间：2021/05/24 Morphinans  arylacetamidyl substituent  kappa opioid receptor modulators  structure-activity relationships   7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263 作者:  Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun 收藏  |  浏览/下载：82/0  |  提交时间：2019/01/08 7 beta-Methyl-nepenthone analogues  KOR ligands  Concept of hybridization  Opioid receptor binding and functional activities   7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14 作者:  Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun 收藏  |  浏览/下载：11/0  |  提交时间：2019/12/05 7 beta-Methyl-nepenthone analogues  KOR ligands  Concept of hybridization  Opioid receptor binding and functional activities   The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent kappa-Opioid Agonistic Activities 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 4, 页码: 766-776 作者:  Li, Wei;  Long, Jian-Dong;  Qian, Yuan-Yuan;  Long, Yu;  Xu, Xue-Jun 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 kappa-opioid receptor  mu-opioid receptor  nepenthones  4,5-epoxymorphinans  pharmacological heterogeneity  structure activity relationship  binding structure