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北京大学 [5]
上海生物化学与细胞生... [4]
厦门大学 [3]
上海药物研究所 [3]
中国科学院大学 [3]
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期刊论文 [43]
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Anti-inflammatory activity of Anchusa italica Retz. in LPS-stimulated RAW264.7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling pathways
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 286, 期号: 3, 页码: 1-9
作者:
Duan, XM (Duan, Xiaomei) [1] , [2]
;
Li, J (Li, Jun) [1] , [2]
;
Cui, JX (Cui, Jingxue) [1] , [2]
;
Dong, YW (Dong, Yuwei) [1] , [2]
;
Xin, XL (Xin, Xuelei) [1] , [2]
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/05/17
Boraginaceae
Anchusa italica Retz.
Anti-inflammatory
Properties and gene expression profiling of acquired radioresistance in mouse breast cancer cells
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9
作者:
Qin, Feng
;
Fan, Qiang
;
Yu, Peter K. N.
;
Almahi, Waleed Abdelbagi
;
Kong, Peizhong
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  |  
浏览/下载:96/0
  |  
提交时间:2021/06/15
Breast cancer
acquired radioresistance
gene expression profiling
energy metabolism
NOD-like receptors in autoimmune diseases
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 15
作者:
Chen, Li
;
Cao, Shi-qi
;
Lin, Ze-min
;
He, Shi-jun
;
Zuo, Jian-ping
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
pattern recognition receptors
NOD-like receptors
autoimmune diseases
inflammasomes
inhibitors
botanicals
Transplantation of GMP-grade human iPSC-derived retinal pigment epithelial cells in rodent model: the first pre-clinical study for safety and efficacy in China
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9
作者:
Zhang, Hang
;
Su, Bingnan
;
Jiao, Luyan
;
Xu, Ze-Hua
;
Zhang, Chang-Jun
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  |  
浏览/下载:45/0
  |  
提交时间:2021/05/31
GMP grade
human iPSCs
RPE cells
pre-clinical study
transplantation
tumorigenicity
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yang, Fang-ming
;
Fan, Di
;
Yang, Xiao-qian
;
Zhu, Feng-hua
;
Shao, Mei-juan
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  |  
浏览/下载:30/0
  |  
提交时间:2020/12/24
dry eye disease
artemisinin derivative
beta-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
Inflammatory cytokines derived from peripheral blood contribute to the modified electroconvulsive therapy-induced cognitive deficits in major depressive disorder
期刊论文
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 2020
作者:
Tian, Haihua
;
Li, Guangxue
;
Xu, Guoan
;
Liu, Jimeng
;
Wan, Xiaohan
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  |  
浏览/下载:22/0
  |  
提交时间:2020/12/16
LONG-TERM POTENTIATION
ALZHEIMERS-DISEASE
SERUM-LEVELS
KAPPA-B
NLRP3
INTERLEUKIN-18
MEMORY
PATHWAY
BRAIN
CELLS
Aeschynomene indica-Nodulating Rhizobia Lacking Nod Factor Synthesis Genes: Diversity and Evolution in Shandong Peninsula, China
期刊论文
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2019, 卷号: 85, 期号: 22, 页码: e00782-19
作者:
Zhang, ZP
;
Li, Y
;
Pan, XH
;
Shao, S
;
Liu, W
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/08
Aeschynomene indica
Rhizobium
genetic diversity
stem nodule
photosynthetic genes
molecular evolution
evolution
H-1 NMR characterization of chitin tetrasaccharide in binary H2O:DMSO solution: Evidence for anomeric end-effect propagation
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 129, 页码: 744-749
作者:
Li, Kecheng
;
Green, Andrew R.
;
Dinges, Meredith M.
;
Larive, Cynthia K.
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/08/28
Chitin
Structure characterization
Amide proton
Binary solvent
End-effect
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation
期刊论文
2019, 卷号: 212, 页码: 36-53
作者:
Ai Q D
;
Chen Chen
;
Chu Shifeng
;
Zhang Zhao
;
Luo Yun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain
BCA = bicinchoninic acid
BSA = bovine serum albumin
CCA = common carotid artery
CCR4 = C-C chemokine receptor type 4
CKLF1 = chemokine-like factor 1
CO-IP = coimmunoprecipitation
ECA = external carotid artery
ELISA = enzyme-linked immunosorbent assay
FDA = Food and Drug Administration
I/R = ischemic/reperfusion
ICA = internal carotid artery
IL-18 = interleukin 18
IL-1β = interleukin 1β
LDH = lactate dehydrogenase
NLRP3 = NOD-like receptor protein 3
PBS = phosphate-buffered saline
SD = standard deviation
TNF-α = tumor necrosis factor α
TTC = 2
3
5-triphenyltetrazolium-chloride
WT = wild-type
pMCAO = permanent middle cerebral artery occlusion
pro-Caspase-1 = precursor Caspase-1
qPCR = quantitative real-time PCR
tMCAO = transient middle cerebral artery occlusion
tPA = tissue plasminogen activator
Coptisine from Coptis chinensis blocks NLRP3 inflammasome activation by inhibiting caspase-1
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 147, 页码: 104348
作者:
Wu, Jiasi
;
Luo, Yu
;
Jiang, Qing
;
Li, Sheng
;
Huang, Wenge
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  |  
浏览/下载:18/0
  |  
提交时间:2021/11/10
Coptisine
Caspase-1
NLRP3 inflammasome
NF-Kb
Gout
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