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科研机构
北京大学 [4]
湖南大学 [3]
上海药物研究所 [2]
山东大学 [2]
中国科学院大学 [1]
四川大学 [1]
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期刊论文 [19]
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2020 [2]
2019 [3]
2018 [1]
2017 [1]
2016 [1]
2015 [2]
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Cell Biolo... [1]
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Harnessing the targeting potential of differential radiobiological effects of photon versus particle radiation for cancer treatment
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2020, 页码: 17
作者:
Zhang, Jinhua
;
Si, Jing
;
Gan, Lu
;
Zhou, Rong
;
Guo, Menghuan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/01/12
DNA damage
DNA repair
particle therapy
photon therapy
radiosensitizer
A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression
期刊论文
CANCER RESEARCH, 2020, 卷号: 80, 期号: 3, 页码: 536-548
作者:
Wang, Yingcong
;
Huang, Jing
;
Li, Bo
;
Xue, Han
;
Tricot, Guido
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
Nonhomologous end joining key factor XLF enhances both 5-florouracil and oxaliplatin resistance in colorectal cancer
期刊论文
ONCOTARGETS AND THERAPY, 2019, 卷号: 12
作者:
Liu, Zhuo
;
Yu, Miao
;
Fei, Bingyuan
;
Sun, Jing
;
Wang, Dongxin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
XLF
nonhomologous end joining
5-florouracil
oxaliplatin
chemoresistance
colorectal cancer
Genistein‐induced DNA damage is repaired by nonhomologous end joining and homologous recombination in TK6 cells
期刊论文
Journal of Cellular Physiology, 2019, 卷号: Vol.234 No.3, 页码: 2683-2692
作者:
Xiaoqing Hu
;
Xiaohua Wu
;
Hao Liu
;
Ziyuan Cheng
;
Zilu Zhao
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/13
DNA
damage
genistein
(GES)
homologous
recombination
(HR)
non‐homologous
DNA
end
joining
(NHEJ)
Genistein-induced DNA damage is repaired by nonhomologous end joining and homologous recombination in TK6 cells
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: Vol.234 No.3, 页码: 2683-2692
作者:
Hu, Xiaoqing
;
Wu, Xiaohua
;
Liu, Hao
;
Cheng, Ziyuan
;
Zhao, Zilu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/17
DNA
damage
genistein
(GES)
homologous
recombination
(HR)
non-homologous
DNA
end
joining
(NHEJ)
Mangiferin induces radiosensitization in glioblastoma cells by inhibiting nonhomologous end joining
期刊论文
ONCOLOGY REPORTS, 2018, 卷号: Vol.40 No.6, 页码: 3663-3673
作者:
Mu, Faguang
;
Liu, Ting
;
Zheng, Hanrui
;
Xie, Xiaofang
;
Lei, Tiantian
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/26
glioblastoma
multiforme
mangiferin
non-homologous
end-joining
homologous
recombination
Cryo-EM structure of the DNA-PK holoenzyme
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017
Sharif, Humayun
;
Li, Yang
;
Dong, Yuanchen
;
Dong, Liyi
;
Wang, Wei Li
;
Mao, Youdong
;
Wu, Hao
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2017/12/03
DNA repair
V(D)J recombination
NHEJ
cryo-EM
structure
DEPENDENT PROTEIN-KINASE
STRAND BREAK REPAIR
3-DIMENSIONAL STRUCTURE
ELECTRON-MICROSCOPY
CATALYTIC SUBUNIT
KU
COMPLEX
END
MECHANISM
SUGGESTS
Simultaneous generation of multi-gene knockouts in human cells
期刊论文
FEBS LETTERS, 2016
Zhou, Yuexin
;
Zhang, Hongmin
;
Wei, Wensheng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
CRISPR
knockout
nonhomologous end-joining
NUCLEASE-INDUCED MUTATIONS
ZINC-FINGER NUCLEASES
STRAND BREAK REPAIR
CRISPR-CAS9 SYSTEM
INSERTION SITES
DNA
CRISPR/CAS9
INTEGRATION
ENRICHMENT
EFFECTORS
Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells
期刊论文
细胞研究英文版, 2015
Wu, Yuxuan
;
Zhou, Hai
;
Fan, Xiaoying
;
Zhang, Ying
;
Zhang, Man
;
Wang, Yinghua
;
Xie, Zhenfei
;
Bai, Meizhu
;
Yin, Qi
;
Liang, Dan
;
Tang, Wei
;
Liao, Jiaoyang
;
Zhou, Chikai
;
Liu, Wujuan
;
Zhu, Ping
;
Guo, Hongshan
;
Pan, Hong
;
Wu, Chunlian
;
Shi, Huijuan
;
Wu, Ligang
;
Tang, Fuchou
;
Li, Jinsong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/13
CRISPR-Cas9
spermatogonial stem cell
gene therapy
GERMLINE TRANSMISSION
IN-VITRO
MUSCULAR-DYSTROPHY
CAS9 NUCLEASE
MODIFIED MICE
SELF-RENEWAL
C-KIT
GENOME
GENERATION
CULTURE
Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells
期刊论文
CELL RESEARCH, 2015, 卷号: 25, 期号: 1, 页码: 67-79
作者:
Wu, YX
;
Zhou, H
;
Fan, XY
;
Zhang, Y
;
Zhang, M
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2015/07/22
CRISPR-Cas9
spermatogonial stem cell
gene therapy
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