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上海药物研究所 [14]
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期刊论文 [32]
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leflunomideincreasedtherenalexposureofacyclovirbyinhibitingoat13andmrp2
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 1, 页码: 129
作者:
Liao Xiaoying
;
Deng Qiangqiang
;
Han Li
;
Wu Zhitao
;
Peng Zhaoliang
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drugdrug interaction
pharmacokinetics
Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 1, 页码: 129-137
作者:
Liao, Xiao-ying
;
Deng, Qiang-qiang
;
Han, Li
;
Wu, Zhi-tao
;
Peng, Zhao-liang
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  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drug-drug interaction
pharmacokinetics
Enhancement of cisplatin efficacy by lipid-CaO2 nanocarrier-mediated comprehensive modulation of the tumor microenvironment
期刊论文
BIOMATERIALS SCIENCE, 2019, 卷号: 7, 期号: 10, 页码: 4260-4272
作者:
He, Chuanchuan
;
Zhang, Xiaojuan
;
Yan, Ruicong
;
Zhao, Pengxuan
;
Chen, Yan
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  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Quercetin and kaempferol increase the intestinal absorption of isorhamnetin coexisting in Elaeagnus rhamnoides (L.) A. Nelson (Elaeagnaceae) extracts via regulating multidrug resistance-associated protein 2
期刊论文
PHYTOMEDICINE, 2019, 卷号: 53
作者:
Xiao Yi
;
Xin Lei
;
Li Lujia
;
Li Guowen
;
Shi Xiufeng
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/05
Isorhamnetin
Flavonoids
Intestinal absorption
Multidrug resistance-associated protein 2 (MRP2)
Elaeagnus rhamnoides (L.) A. nelson (elaeagnaceae)
Intra-herb interaction
Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:
Dong, Jiajia
;
Olaleye, Olajide E.
;
Jiang, Rongrong
;
Li, Jing
;
Lu, Chuang
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  |  
浏览/下载:103/0
  |  
提交时间:2019/01/08
Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance-Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator-Activated Receptor alpha Activation
期刊论文
MOLECULAR PHARMACOLOGY, 2018, 卷号: 93, 期号: 6, 页码: 563-574
作者:
Wang, Le
;
Ma, Leilei
;
Lin, Yunfei
;
Liu, Xing
;
Xiao, Ling
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  |  
浏览/下载:49/0
  |  
提交时间:2019/01/08
JBP485 attenuates vancomycin-induced nephrotoxicity by regulating the expressions of organic anion transporter (Oat) 1, Oat3, organic cation transporter 2 (Oct2), multidrug resistance-associated protein 2 (Mrp2) and P-glycoprotein (P-gp) in rats
期刊论文
Toxicology Letters, 2018, 卷号: Vol.295, 页码: 195-204
作者:
Shijie Wen
;
Changyuan Wang
;
Xiaokui Huo
;
Qiang Meng
;
Zhihao Liu
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/02/25
Vancomycin
JBP485
Nephrotoxicity
Transporter
Endogenous toxins
Nimesulide and 4 '-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis
期刊论文
DRUG METABOLISM AND DISPOSITION, 2017, 卷号: 45, 期号: 5, 页码: 441-448
作者:
Zhou, Lei
;
Pang, Xiaoyan
;
Jiang, Jingfang
;
Zhong, Dafang
;
Chen, Xiaoyan
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  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
The role of Ntcp, Oatp2, Bsep and Mrp2 in liver injury induced by Dioscorea bulbifera L. and Diosbulbin B in mice
期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2017, 卷号: 51
作者:
Qu, Xiao-Yu
;
Tao, Li-Na
;
Zhang, Si-Xi
;
Sun, Jing-Meng
;
Niu, Jun-Qi
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
Dioscorea bulbifera L.
Diosbulbin B
Na plus -taurocholate co-transporting polypeptide
Organic anion transporting polypeptide 2
Bile salt export pump
Multidrug resistance associated protein 2
Comparison of mercury sulfides with mercury chloride and methylmercury on hepatic P450, phase-2 and transporter gene expression in mice
期刊论文
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, 2016
Xu, S. F.
;
Wu, Q.
;
Zhang, B. B.
;
Li, H.
;
Xu, Y. S.
;
Du, Y. Z.
;
Wei, L. X.
;
Liu, J.
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  |  
浏览/下载:10/0
  |  
提交时间:2019/06/14
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