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Effects of toxin metalloproteinases from jellyfish
Nemopilema
nomurai
nematocyst on the dermal toxicity and potential treatment of jellyfish dermatitis
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 128, 页码: 12
作者:
Li, Aoyu
;
Yu, Huahua
;
Li, Rongfeng
;
Yue, Yang
;
Yu, Chunlin
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/04/07
Inflammation
Jellyfish dermatitis
Jellyfish envenomation
Nemopilema nomurai nematocyst venom (NnNV)
Metalloproteinase
Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Wu, Xiaofan
;
Yang, Hongjian
;
Yu, Xingfei
;
Qin, Jiang-Jiang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/22
HER2
breast cancer
targeted therapy
drug resistance
overcoming strategies
Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China
期刊论文
THORACIC CANCER, 2022
作者:
Xu, Chunwei
;
Si, Lu
;
Wang, Wenxian
;
Li, Ziming
;
Song, Zhengbo
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/12/22
fusion
precision medicine
solid tumor
targeted therapy
tyrosine receptor kinase
Key Considerations in Targeted Protein Degradation Drug Discovery and Development
期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:
Qin, Liena
;
Dai, Han
;
Wang, Junfeng
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
targeted protein degradation
PROTAC
molecular glue
chemically induced proximity
drug discovery and development
Systemic Therapy for Hepatocellular Carcinoma: Chinese Consensus-Based Interdisciplinary Expert Statements
期刊论文
LIVER CANCER, 2022, 卷号: 11
作者:
Sun, Yongkun
;
Zhang, Wen
;
Bi, Xinyu
;
Yang, Zhengqiang
;
Tang, Yu
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/12/23
Chinese interdisciplinary experts
Hepatocellular carcinoma
Molecular targeted therapy
Consensus
Application of Noninvasive Imaging to Combined Immune Checkpoint Inhibitors for Breast Cancer: Facts and Future
期刊论文
MOLECULAR IMAGING AND BIOLOGY, 2022, 页码: 16
作者:
Cheng, Zhongquan
;
Du, Yang
;
Yu, Leyi
;
Yuan, Zhu
;
Tian, Jie
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/03/17
Noninvasive imaging
Immune checkpoint inhibitor
Combined immunotherapy
Breast cancer
An overview of kinase downregulators and recent advances in discovery approaches
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:
Wang, Beilei
;
Wu, Hong
;
Hu, Chen
;
Wang, Haizhen
;
Liu, Jing
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/01/25
Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:
Su, Haixia
;
Yao, Sheng
;
Zhao, Wenfeng
;
Zhang, Yumin
;
Liu, Jia
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/08/17
A novel low systemic diacylglycerol acyltransferase 1 inhibitor, Yhhu2407, improves lipid metabolism
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 卷号: 158, 页码: 9
作者:
Huang, Jun-Shang
;
Guo, Bin-Bin
;
Lin, Fei-Fei
;
Zeng, Li-Min
;
Wang, Ting
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
DGAT1
Inhibitor
Pharmacokinetics
Dyslipidemia
Lipid metabolism
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Li, Yalei
;
Wang, Juan
;
Ding, Huaqian
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
Medulloblastoma
Hedgehog signaling
pathway
Drug resistance
GLI
BRD4
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