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大连化学物理研究所 [34]
上海药物研究所 [26]
厦门大学 [6]
北京大学 [5]
大连理工大学 [4]
中国科学院大学 [3]
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浏览/检索结果:
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Gut microbiota: An emerging therapeutic approach of herbal medicine for prevention of colorectal cancer
期刊论文
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, 卷号: 12
作者:
Ying, Hua-Zhong
;
Xie, Wei
;
Wang, Meng-Chuan
;
He, Jia-Qi
;
Zhang, Huan-Huan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/23
intestinal homeostasis
natural products
chronic inflammation
probiotic
immunoenhancement
tumor microenvironment
Characterization of the metabolites of tirabrutinib generated from rat, dog and human liver microsomes using ultra-high-performance liquid chromatography combined with high-resolution mass spectrometry
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2022, 卷号: 36
作者:
Zhang, Hongjian
;
Hu, Zhen
;
Zhang, Huiping
;
Sun, Xiyan
;
Yang, Jianming
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/03/28
A five-dimensional data collection strategy for multicomponent discovery and characterization in Traditional Chinese Medicine: Gastrodia Rhizoma as a case study
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1653, 页码: 12
作者:
Zhu, Haodong
;
Wu, Xingdong
;
Huo, Jiangyan
;
Hou, Jinjun
;
Long, Huali
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2021/11/04
Gastrodia Rhizoma
Multidimensional data acquisition
Offline 2D-LC-IMS-DIA MS
MS
Neutral loss (NLs)
Collision cross section (CCS)
Comprehensively feature-based molecular networking and metabolomics approaches to reveal the differences components in Cinnamomum cassia and Cinnamomum verum
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 12
作者:
Wu, Xingdong
;
Long, Huali
;
Li, Feifei
;
Wu, Wenyong
;
Zhou, Jing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
alkaloids
Cinnamomum
feature-based molecular networking
metabolite profiling
proanthocyanidins
Absorption, distribution, metabolism, and excretion of [C-14]NBP (3-n-butylphthalide) in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 9
作者:
Tian, Junjun
;
Lei, Peng
;
He, Yifei
;
Zhang, Ning
;
Ge, Xinyu
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
3-n-butylphthalide (NBP)
[C-14]NBP
Pharmacokinetics
Tissue distribution
Metabolism
Mass balance
Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483
作者:
Huang, Huoming
;
Li, Xueping
;
Xie, Peng
;
Li, Xinwei
;
Xu, XueJun
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/08/17
Metabolic Study of Stable Isotope Labeled Indolinone Derivative in Hepatocyte Cell by UPLC/Q TOF MS
期刊论文
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2021, 卷号: 32, 期号: 6, 页码: 1538-1544
作者:
Yang, Jixia
;
Zhang, Gongzheng
;
Wang, Zhaoyang
;
Meng, Jian
;
Wen, Hongliang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/12/16
indolinone derivatives
alpha-synuclein
[C-3(2), N-15]-isotope labeling, metabolite
UPLC/QTOF
Isolation and identification of antimicrobial metabolites from sea anemone-derived fungus Emericella sp. SMA01
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2021, 页码: 10
作者:
Yue, Yang
;
Yu, Huahua
;
Li, Rongfeng
;
Hu, Linfeng
;
Liu, Song
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/04/14
sea anemone
symbiotic fungi
phenazine-1-carboxylic acid
antimicrobial activity
Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective mu Opioid Receptor Agonists
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 2, 页码: 285-299
作者:
Huang, Huoming
;
Li, Xinwei
;
Guo, Wei
;
Zhu, Chen
;
Qian, Yuanyuan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
pain
opioid analgesic
SAR
selective MOR agonist
molecular dynamics simulations
A Versatile Transcription-Translation in One Approach for Activation of Cryptic Biosynthetic Gene Clusters
期刊论文
ACS CHEMICAL BIOLOGY, 2020, 卷号: 15, 期号: 9, 页码: 2551-2557
作者:
Zhang, Qian
;
Ren, Jin-Wei
;
Wang, Weishan
;
Zhai, Ji'an
;
Yang, Jing
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/17
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