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科研机构
复旦大学上海医学院 [4]
上海药物研究所 [2]
中南大学 [2]
兰州大学 [1]
上海微系统与信息技术... [1]
武汉大学 [1]
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期刊论文 [13]
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2020 [1]
2018 [2]
2017 [1]
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chemistry [1]
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Pharmacophore-Based Virtual Screening Toward the Discovery of Novel Anti-echinococcal Compounds
期刊论文
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2020, 卷号: 10, 页码: 12
作者:
Liu, Congshan
;
Yin, Jianhai
;
Yao, Jiaqing
;
Xu, Zhijian
;
Tao, Yi
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
echinococcosis
Echinococcus multilocularis
pharmacophore modeling
virtual screenings
in vitro drug screen
cytotoxicity
E
multilocularis-infected mice
pharmacokinetics analysis
Mefloquine targets beta-catenin pathway and thus can play a role in the treatment of liver cancer
期刊论文
MICROBIAL PATHOGENESIS, 2018, 卷号: 118
作者:
Zhang, Guo-Feng
;
Wu, Jia-Cheng
;
Gong, Lu-Lu
;
Lin, Rui-Xin
;
Ming-Zhong
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Antimalarial drug mefloquine inhibits nuclear factor kappa B signaling and induces apoptosis in colorectal cancer cells
期刊论文
2018, 卷号: 109, 期号: 4, 页码: 1220-1229
作者:
Xu, Xin
;
Wang, Jun
;
Han, Kunkun
;
Li, Shaoyan
;
Xu, Feng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
colorectal cancer
drug repurpose
mefloquine
NF-B
therapy
Therapeutic effects of antibiotic drug mefloquine against cervical cancer through impairing mitochondrial function and inhibiting mTOR pathway
期刊论文
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2017, 卷号: 95, 期号: 1
作者:
Li, Hui
;
Jiao, Shun
;
Li, Xin
;
Banu, Hasina
;
Hamal, Shreejana
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
cervical cancer
mefloquine
mitochondrial respiration
mTOR signaling
Considerations in the Repositioning of Mefloquine for Anesthetic Indications Reply
期刊论文
ANESTHESIOLOGY, 2016, 卷号: 125, 期号: 1
作者:
Wang, Ying-Wei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/06
Mefloquine inhibits chondrocytic proliferation by arresting cell cycle in G2/M phase
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2015, 卷号: 8, 期号: 10
作者:
Li, Qiong
;
Chen, Zeng-Gan
;
Xia, Qing
;
Lin, Jian-Ping
;
Yan, Zuo-Qin
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/19
Chondrocytes
mefloquine
proliferation
inhibition
cyclin B1
In vivo and in vitro efficacies of mebendazole, mefloquine and nitazoxanide against cyst echinococcosis
期刊论文
PARASITOLOGY RESEARCH, 2015, 卷号: 114, 期号: 6
作者:
Liu, Congshan
;
Zhang, Haobing
;
Yin, Jianhai
;
Hu, Wei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
Mebendazole
Mefloquine
Nitazoxanide
Tizoxanide
Protoscoleces
Germinal cell
Treatment efficacy
Addition of Exogenous NAD+ Prevents Mefloquine-Induced Neuroaxonal and Hair Cell Degeneration through Reduction of Caspase-3-Mediated Apoptosis in Cochlear Organotypic Cultures
期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 11, 页码: e79817
作者:
Ding, Dalian
;
Qi, Weidong
;
Yu, Dongzhen
;
Jiang, Haiyan
;
Han, Chul
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
Neurons,Auditory nerves,Cochlea,Ganglia,Nerve fibers,Neuronal tuning,Apoptosis,Oxidative stress
Addition of Exogenous NAD(+) Prevents Mefloquine-Induced Neuroaxonal and Hair Cell Degeneration through Reduction of Caspase-3-Mediated Apoptosis in Cochlear Organotypic Cultures
期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 11
作者:
Ding, Dalian
;
Qi, Weidong
;
Yu, Dongzhen
;
Jiang, Haiyan
;
Han, Chul
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
Mefloquine Damage Vestibular Hair Cells in Organotypic Cultures
期刊论文
Neurotoxicity Research, 2011, 卷号: 20, 期号: 1, 页码: 51-58
作者:
Yu, Dongzhen
;
Ding, Dalian
;
Jiang, Haiyan
;
Stolzberg, Daniel
;
Salvi, Richard*
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
Caspase-3
Caspase-8
Caspase-9
Hair cells
Mefloquine
Utricles
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