CORC

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CORC

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Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:  Zhang, Feng-cai;  Sun, Zhong-ya;  Liao, Li-ping;  Zuo, Yu;  Zhang, Dan
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:  Zhang Fengcai;  Sun Zhongya;  Liao Liping;  Zuo Yu;  Zhang Dan
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/01
The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein-Protein Interaction 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 33, 页码: 5530-5542
作者:  Ye, Xiaoqing;  Chen, Gang;  Jin, Jia;  Zhang, Binzhong;  Wang, Yinda
收藏  |  浏览/下载：15/0  |  提交时间：2020/12/24
The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 4, 页码: 638-645
作者:  Ye, Xiaoqing;  Zhang, Rukang;  Lian, Fulin;  Zhang, Weiyao;  Lu, Wenchao
收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01
Disruption of the menin-MLL interaction triggers menin protein degradation via ubiquitin-proteasome pathway 期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2019, 卷号: 9, 期号: 8
作者:  Wu, Yuan;  Doepner, Miriam;  Hojnacki, Taylor;  Feng, Zijie;  Katona, Bryson W.
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/05
CDKI-73: an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia 期刊论文
INVESTIGATIONAL NEW DRUGS, 2019, 卷号: 37, 期号: 4, 页码: 625-635
作者:  Rahaman, Muhammed H.;  Yu, Yingyi;  Zhong, Longjin;  Adams, Julian;  Lam, Frankie
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
Melatonin inhibits MLL-rearranged leukemia via RBFOX3/hTERT and NF-κB/COX-2 signaling pathways 期刊论文
Cancer Letters, 2019, 卷号: Vol.443 No.1, 页码: 167-178
作者:  Tang, Yan-Lai;  Sun, Xi;  Huang, Li-Bin;  Liu, Xiao-Jian;  Qin, Ge
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/17
Six1 regulates leukemia stem cell maintenance in acute myeloid leukemia 期刊论文
2019, 卷号: 110, 期号: 7, 页码: 2200-2210
作者:  Chu Yajing;  Chen Yangpeng;  Li Mengke;  Shi Deyang;  Wang Bichen
收藏  |  浏览/下载：12/0  |  提交时间：2020/01/03
Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 80, 页码: 649-654
作者:  Zhang, Li;  Chen, Yantao;  Liu, Na;  Li, Linjuan;  Xiao, Senhao
收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08
Design, synthesis and biological evaluation of benzo[cd]indo1-2(1H)-ones derivatives as BRD4 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 264-273
作者:  Feng, Yuxin;  Xiao, Senhao;  Chen, Yantao;  Jiang, Hao;  Liu, Na
收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08

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