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上海药物研究所 [6]
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期刊论文 [26]
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浏览/检索结果:
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1 beta-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-kappa B pathway
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 101
作者:
Yu, Bing
;
Jin, Xiao-Qing
;
Yu, Wen-Ying
;
Dong, Ying-Ying
;
Ying, Hua-Zhong
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/01/10
Sesquiterpene lactone
Flavonoid
Cell apoptosis
ROS
JNK
FOXO1
Up-regulation of THY1 attenuates interstitial pulmonary fibrosis and promotes lung fibroblast apoptosis during acute interstitial pneumonia by blockade of the WNT signaling pathway.
期刊论文
Cell cycle (Georgetown, Tex.), 2019, 页码: 1-12
作者:
Lin Chen
;
Rong-Zhen Tang
;
Jia Ruan
;
Xiao-Bo Zhu
;
Yang Yang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/17
Thymocyte differentiation antigen-1
WNT signaling pathway
acute interstitial pneumonia
lung fibroblast
proliferation
pulmonary fibrosis
The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors
期刊论文
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:
Wang, Xinyi
;
Ai, Jing
;
Liu, Hongyan
;
Peng, Xia
;
Chen, Hui
收藏
  |  
浏览/下载:138/0
  |  
提交时间:2019/01/08
1,4-Diaryl-2-azetidinone
Combretastatin A-4
Tubulin polymerization
Antitumor
SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 243-250
作者:
Jiang, Xi-fei
;
Dai, Yang
;
Peng, Xia
;
Shen, Yan-yan
;
Su, Yi
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
human cancer
anticancer drug
SOMCL-085
receptor tyrosine kinase
FGFR
xenograft nude mouse model
Effects of Ginkgo biloba leaf extract, shenmai and matrine on a human embryonic lung fibroblast fibrosis model
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 卷号: 16, 期号: 5, 页码: 4289-4295
作者:
Zhang, Xingcai
;
Cai, Yuli
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  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
transforming growth factor-beta
human embryonic lung fibroblasts
Ginkgo biloba leaf extract
shenmai
matrine
pulmonary fibrosis
cell
proliferation
apoptosis
collagen type I
collagen type III
alpha-smooth muscle actin
extracellular superoxide dismutase
somcl085anovelmultitargetedfgfrinhibitordisplayspotentanticanceractivityinfgfraddictedhumancancermodels
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 2, 页码: 243
作者:
Jiang Xifei
;
Dai Yang
;
Peng Xia
;
Shen Yanyan
;
Su Yi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/07/01
human cancer
anticancer drug
SOMCL-085
receptor tyrosine kinase
FGFR
xenograft nude mouse model
Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532
作者:
Chen, Wen-hua
;
Song, Shan-shan
;
Qi, Ming-hui
;
Huan, Xia-juan
;
Wang, Ying-qing
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  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
PARP-1 inhibitor
olaparib
breast cancer
BRCA-deficient tumors
Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-kappa B signaling pathway
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Li, Chengcheng
;
Yu, Yan
;
Li, Wenjun
;
Liu, Bo
;
Jiao, Xudong
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2017/09/05
RhoA/ROCK1 signaling pathway is involved in proliferation and differentiation in human lung fibroblast cells
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2017, 卷号: 10, 期号: 5, 页码: 6170-6178
作者:
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
Pulmonary fibrosis
MRC-5 cells
RhoA/ROCK1 signaling pathway
proliferation
differentiation
discoveryofpotent24difluorolinkerpolyadpribosepolymerase1inhibitorswithenhancedwatersolubilityandinvivoanticancerefficacy
期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 11, 页码: 1521
作者:
Chen Wenhua
;
Song Shanshan
;
Ql Minghui
;
Huan Xiajuan
;
Wang Yingqing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
PARP INHIBITORS
MEDICINAL CHEMISTRY
DRUG DISCOVERY
CANCER
THERAPY
DESIGN
FLUORINE
SUCCESS
PREDICT
METRICS
PARP-1 inhibitor
olaparib
breast cancer
BRCA-deficient tumors
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