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Bldesin, the first functionally characterized pathogenic fungus defensin with Kv1.3 channel and chymotrypsin inhibitory activities
期刊论文
Journal of Biochemical and Molecular Toxicology, 2019, 卷号: Vol.33 No.2
作者:
Xudong Luo
;
Wen Zhu
;
Li Ding
;
Xiangdong Ye
;
Huanhuan Gao
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/17
channel
inhibitor
CSα/β
defensin
pathogenic
fungus
protease
inhibitor
Three new phenylspirodrimane derivatives with inhibitory effect towards potassium channel Kv1.3 from the fungus Stachybotrys chartarum
期刊论文
2019, 卷号: 21, 期号: 9, 页码: 887-894
作者:
Feng, Jia-Min
;
Li, Min
;
Zhao, Jin-Lian
;
Jia, Xiao-Na
;
Liu, Ji-Mei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Phenylspirodrimanes derivatives
Stachybotrys chartarum
potassium channel Kv1
3
Pharmacological characterization of human beta-defensins 3 and 4 on potassium channels: Evidence of diversity in beta-defensin-potassium channel interactions
期刊论文
PEPTIDES, 2018, 卷号: 108
作者:
Zhao, Yonghui
;
Xie, Zili
;
Feng, Jing
;
Li, Wenxin
;
Gao, Zhijian
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
beta-Defensin
Potassium channel
Kv1.3 channel
Pore-blocking
Interaction mode
Interaction mechanism
A Kv1.3 channel-specific blocker alleviates neurological impairment through inhibiting T-cell activation in experimental autoimmune encephalomyelitis
期刊论文
CNS NEUROSCIENCE & THERAPEUTICS, 2018, 卷号: 24, 期号: 10
作者:
Yuan, Xiao-Lu
;
Zhao, Yi-Peng
;
Huang, Jie
;
Liu, Jun-Chen
;
Mao, Wen-Qian
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  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
EAE
immunomodulation
Kv1
3 channel
multiple sclerosis
neuroprotection
The Kv1.3 channel-inhibitory toxin BF9 also displays anticoagulant activity via inhibition of factor XIa
期刊论文
TOXICON, 2018, 卷号: Vol.152, 页码: 9-15
作者:
Ding, Li
;
Hao, Jinbo
;
Luo, Xudong
;
Zhu, Wen
;
Wu, Zheng
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/26
Kv1.3
channel
Factor
XIa
Structural
fold
Kunitz-type
Anticoagulation
Cloning, expression and identification of KTX-Sp4, a selective Kv1.3 peptidic blocker from Scorpiops pococki
期刊论文
Cell & Bioscience, 2017, 卷号: 7, 期号: 1
作者:
Zou,Yan
;
Zhang,Feng
;
Li,Yaxian
;
Wang,Yuanfang
;
Li,Yi
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2018/09/27
Peptide KTX-Sp4
Scorpiops pococki
Kv1.3
Channel turret
Selectivity
Molecular characterization and functional analysis of four teleostean K+ channels in macrophages of sea perch (Lateolabrax japonicas)
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 60, 页码: 426-435
作者:
Cong, Bailin
;
Chai, Yingmei
;
Wang, Bo
;
Liu, Shenghao
;
Shen, Jihong
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  |  
浏览/下载:5/0
  |  
提交时间:2019/08/19
Voltage-gated potassium ion channels
Sea perch Lateolabrax japonicas
Macrophages
LPS
Immune function
Discovery of three toxin peptides with Kv1.3 channel and IL-2 cytokine-inhibiting activities from Non-Buthidae scorpions, Chaerilus tricostatus and Chaerilus tryznai
期刊论文
PEPTIDES, 2017, 卷号: 91
作者:
Ding, Li
;
Chen, Jing
;
Hao, Jinbo
;
Zhang, Jiahui
;
Huang, Xuejun
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Chaerilidae
Kv1.3 channel
Scorpion toxin
IL-2
Potential immunoregulatory peptide
Kv1.3 channel blocker (ImKTx88) maintains blood-brain barrier in experimental autoimmune encephalomyelitis
期刊论文
CELL AND BIOSCIENCE, 2017, 卷号: 7
作者:
Huang, Jie
;
Han, Song
;
Sun, Qi
;
Zhao, Yipeng
;
Liu, Junchen
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
Kv1.3 channel blocker
Blood-brain barrier
Experimental autoimmune encephalomyelitis
Multiple sclerosis
IL-17
Feeling Nature's PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS)
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 3, 页码: 616-628
Baell, JB
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浏览/下载:53/0
  |  
提交时间:2017/01/12
POTASSIUM CHANNEL KV1.3
CLINICAL-TRIALS
CRYSTAL-STRUCTURE
TOXICOLOGICAL EVALUATION
CHEMICAL-PROPERTIES
REACTIVE COMPOUNDS
MOLECULAR-BASIS
VITAMIN-K
DISCOVERY
INHIBITORS
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