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Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:  Gao, Dingding;  Jin, Nan;  Fu, Yixian;  Zhu, Yueyue;  Wang, Yujie
收藏  |  浏览/下载:43/0  |  提交时间:2021/06/11
Inhibition of Tumor Lymphangiogenesis is an Important Part that EGFR-TKIs Play in the Treatment of NSCLC 期刊论文
JOURNAL OF CANCER, 2020, 卷号: 11, 期号: 1, 页码: 241-250
作者:  Zhang, Yan;  Yang, Xinying;  Liu, Hongchun;  Cai, Minghui;  Yang Shentu
收藏  |  浏览/下载:29/0  |  提交时间:2020/07/01
3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01
Profibrotic effect of IL-17A and elevated IL-17RA in idiopathic pulmonary fibrosis and rheumatoid arthritis-associated lung disease support a direct role for IL-17A/IL-17RA in human fibrotic interstitial lung disease 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2019, 卷号: 316, 期号: 3
作者:  Zhang, Jie;  Wang, Dan;  Wang, Lei;  Wang, Shaohua;  Roden, Anja C.
收藏  |  浏览/下载:24/0  |  提交时间:2019/12/05
Pro-fibrotic effects of IL-17A and elevated IL-17RA in IPF and RA-ILD support a direct role for IL-17A/IL-17RA in human fibrotic interstitial lung disease 期刊论文
American journal of physiology. Lung cellular and molecular physiology, 2019
作者:  Zhang Jie[1];  Wang Dan[2];  Wang Lei[3];  Wang Shaohua[4];  Roden Anja C[5]
收藏  |  浏览/下载:31/0  |  提交时间:2019/04/22
Profibrotic effect of IL-17A and elevated IL-17RA in idiopathic pulmonary fibrosis and rheumatoid arthritis-associated lung disease support a direct role for IL-17A/IL-17RA in human fibrotic interstitial lung disease 期刊论文
American journal of physiology. Lung cellular and molecular physiology, 2019, 卷号: 316, 页码: L487-L497
作者:  Zhang Jie[1];  Wang Dan[2];  Wang Lei[3]
收藏  |  浏览/下载:33/0  |  提交时间:2019/04/22
3deoxy216dihydroxynagilactoneeanaturalcompoundfrompodocarpusnagipreferentiallyinhibitsjak2stat3signalingbyallostericallyinteractingwiththeregulatorydomainofjak2andinducesapoptosisofcancercells 期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 12, 页码: 1578
作者:  Shan Hui;  Yao Sheng;  Ye Yang;  Yu Qiang
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/01
3-Deoxy-2β,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/ STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
中国药理学报:英文版, 2019, 卷号: 40.0, 期号: 012, 页码: 1578
作者:  Hui Shan;  Sheng Yao;  Yang Ye;  Qiang Yu
收藏  |  浏览/下载:16/0  |  提交时间:2020/12/24
A new xanthatin analogue 1 beta-hydroxyl-5 alpha-chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellular carcinoma 期刊论文
BIOCHIMIE, 2018, 卷号: 152, 期号: 2018, 页码: 43-52
作者:  Fang, Xin-Yi;  Zhang, Hai;  Zhao, Lin;  Tan, Shuai;  Ren, Qing-Cuo
收藏  |  浏览/下载:14/0  |  提交时间:2020/12/24
Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer 期刊论文
CANCER CELL, 2016, 卷号: 30, 期号: 3, 页码: 459-473
作者:  Zeng, Hanlin;  Qu, Jia;  Jin, Nan;  Xu, Jun;  Lin, Chenchu
收藏  |  浏览/下载:23/0  |  提交时间:2019/01/08


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