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北京大学 [6]
上海药物研究所 [4]
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期刊论文 [14]
学位论文 [2]
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New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:
Tian, Qian-Ting
;
Ding, Chun-Yong
;
Song, Shan-Shan
;
Wang, Ying-Qing
;
Zhang, Ao
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Tanshinone-1
S222
S439
Anticancer targets
DNA topoisomerases
P53
Type IA topoisomerases can be "magicians" for both DNA and RNA in all domains of life
期刊论文
RNA BIOLOGY, 2017
Ahmad, Muzammil
;
Xu, Dongyi
;
Wang, Weidong
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  |  
浏览/下载:7/0
  |  
提交时间:2017/12/03
FMRP
polyribosomes
topoisomerase
TDRD3
Top3
Top3
BLOOM-SYNDROME DISSOLVASOME
X-SYNDROME PROTEIN
ESCHERICHIA-COLI
MESSENGER-RNA
III-ALPHA
ESSENTIAL COMPONENT
CELLULAR ROLES
CIRCULAR RNAS
COMPLEX
TDRD3
Thermodynamics and kinetics of TopoII action: A consensus on T-segment curvature selection? Comment on "Disentangling DNA Molecules" by Alexander Vologodskii
期刊论文
PHYSICS OF LIFE REVIEWS, 2016
Chan, Hue Sun
;
Liu, Zhirong
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  |  
浏览/下载:2/0
  |  
提交时间:2017/12/03
TOPOLOGY SIMPLIFICATION
TYPE-2 TOPOISOMERASES
II TOPOISOMERASES
DECATENATION
Consistent rationalization of type-2 topoisomerases' unknotting, decatenating, supercoil-relaxing actions and their scaling relation
期刊论文
JOURNAL OF PHYSICS-CONDENSED MATTER, 2015
Liu, Zhirong
;
Chan, Hue Sun
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  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
wormlike DNA model
writhe
hooked-juxtaposition hypothesis
the bend-angle model
II DNA TOPOISOMERASES
NONEQUILIBRIUM TOPOLOGY SIMPLIFICATION
LOCAL JUXTAPOSITION GEOMETRY
ESCHERICHIA-COLI
CHIRAL DISCRIMINATION
STRUCTURAL BASIS
KNOTS
IV
MECHANISM
SELECTION
Local site preference rationalizes disentangling by DNA topoisomerases
期刊论文
PHYSICAL REVIEW E, 2010, 卷号: 81, 期号: 3
作者:
Liu, Zhirong
;
Zechiedrich, Lynn
;
Chan, Hue Sun
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  |  
浏览/下载:12/0
  |  
提交时间:2019/04/09
Local site preference rationalizes disentangling by DNA topoisomerases
期刊论文
physical review e, 2010
Liu, Zhirong
;
Zechiedrich, Lynn
;
Chan, Hue Sun
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2015/11/13
JUXTAPOSITION GEOMETRY
II TOPOISOMERASES
STRUCTURAL BASIS
CIRCULAR DNA
TOPOLOGY
KNOTS
SIMPLIFICATION
SIMULATIONS
MECHANISM
Action at Hooked or Twisted-Hooked DNA Juxtapositions Rationalizes Unlinking Preference of Type-2 Topoisomerases
期刊论文
分子生物学杂志, 2010
Liu, Zhirong
;
Zechiedrich, Lynn
;
Chan, Hue Sun
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  |  
浏览/下载:2/0
  |  
提交时间:2015/11/10
DNA supercoils
writhe
torsional energy
self-avoiding lattice polygons
Madras-Orlitsky-Shepp algorithm
INTERTWINED CATENATED DIMERS
SELF-AVOIDING WALKS
LATTICE MONTE-CARLO
ESCHERICHIA-COLI
II TOPOISOMERASES
THERMODYNAMIC PROPERTIES
TOPOLOGY SIMPLIFICATION
STATISTICAL-THEORY
SUPERCOILED DNA
WRITHING NUMBER
The why and how of DNA unlinking
期刊论文
核酸研究, 2009
Liu, Zhirong
;
Deibler, Richard W.
;
Chan, Hue Sun
;
Zechiedrich, Lynn
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  |  
浏览/下载:7/0
  |  
提交时间:2015/11/13
SITE-SPECIFIC RECOMBINATION
LOCAL JUXTAPOSITION GEOMETRY
INTERTWINED CATENATED DIMERS
TOPOISOMERASE-II
ESCHERICHIA-COLI
DOUBLE HELIX
CYCLE CHECKPOINT
SUPERCOILED DNA
BUDDING YEAST
TOPOLOGY
The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation
期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2008, 卷号: 71, 期号: 4, 页码: 1984-1994
作者:
Xiong, Bing
;
Burk, David L.
;
Shen, Jianhua
;
Luo, Xiaomin
;
Liu, Hong
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
topoisomerase III
normal mode
steered molecular dynamics
correlation map
protein-DNA interaction
MM-PBSA
R16, a novel amonafide analogue, induces apoptosis and G(2)-M arrest via poisoning topoisomerase II
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2007, 卷号: 6, 期号: 2, 页码: 484-495
作者:
Zhu, Hong
;
Huang, Min
;
Yang, Fan
;
Chen, Yi
;
Miao, Ze-Hong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/01/08
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