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Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei
收藏  |  浏览/下载:16/0  |  提交时间:2022/12/22
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu
收藏  |  浏览/下载:46/0  |  提交时间:2021/08/17
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor 期刊论文
CELL RESEARCH, 2020, 页码: 11
作者:  Sun, Wen;  Chen, Li-Nan;  Zhou, Qingtong;  Zhao, Li-Hua;  Yang, Dehua
收藏  |  浏览/下载:86/0  |  提交时间:2020/12/24
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:  Yuliantie, Elita;  Darbalaei, Sanaz;  Dai, Antao;  Zhao, Peishen;  Yang, Dehua
收藏  |  浏览/下载:22/0  |  提交时间:2020/12/24
Full-length human GLP-1 receptor structure without orthosteric ligands 期刊论文
naturecommunications, 2020, 卷号: 11, 期号: 1, 页码: 1
作者:  Fan Wu;  Linlin Yang;  Kaini Hang;  Mette Laursen;  Lijie Wu
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/01
Combined effect of GABA and glucagon-like peptide-1 receptor agonist on cytokine-induced apoptosis in pancreatic beta-cell line and isolated human islets(sic)beta(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)(sic)GABA(sic)(sic)(sic)(sic)-1(sic)(sic)(sic)(sic)(sic)(sic)(sic)offspring(sic)(sic)(sic)(sic)(sic) 期刊论文
JOURNAL OF DIABETES, 2019, 卷号: 11, 期号: 7
作者:  Son, Dong Ok;  Liu, Wenjuan;  Li, Xiaoming;  Prud'homme, Gerald J.;  Wang, Qinghua
收藏  |  浏览/下载:30/0  |  提交时间:2019/12/05
Evaluating the utility of human glucagon-like peptide 1 receptor gene as a novel radionuclide reporter gene: a promising molecular imaging tool 期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2019, 卷号: 103, 期号: 3
作者:  Pan, Yu;  Lv, Jing;  Pan, Donghui;  Xu, Yuping;  Yang, Min
收藏  |  浏览/下载:21/0  |  提交时间:2019/12/05
Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 212-242
作者:  Dal Maso, Emma;  Zhu, Yue;  Vi Pham;  Reynolds, Christopher A.;  Deganutti, Giuseppe
收藏  |  浏览/下载:41/0  |  提交时间:2019/01/08
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex 期刊论文
NATURE, 2018, 卷号: 555, 期号: 7694, 页码: 121-+
作者:  Liang, Yi-Lynn;  Khoshouei, Maryam;  Glukhova, Alisa;  Furness, Sebastian G. B.;  Zhao, Peishen
收藏  |  浏览/下载:38/0  |  提交时间:2019/01/08
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators 期刊论文
NATURE, 2017, 卷号: 546, 期号: 7657, 页码: 312-+
作者:  Song, Gaojie;  Yang, Dehua;  Wang, Yuxia;  de Graaf, Chris;  Zhou, Qingtong
收藏  |  浏览/下载:31/0  |  提交时间:2019/01/08


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