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Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 3, 2020, 卷号: 320, 页码: G272-G282
作者:  Li W(李旺);  Li PW(李培文);  Li N(李宁);  Du Y(杜宇);  Lv SQ(吕守芹)
收藏  |  浏览/下载:9/0  |  提交时间:2022/10/25
18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway 期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:  Wu, Shou-Yan;  Cui, Shi-Chao;  Wang, Le;  Zhang, Yi-Ting;  Yan, Xiao-Xia
收藏  |  浏览/下载:96/0  |  提交时间:2019/01/08
18 beta-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:  Wu, Shou-yan;  Cui, Shi-chao;  Wang, Le;  Zhang, Yi-ying;  Yan, Xiao-xia
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/01
The HNF1 alpha-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1 期刊论文
MOLECULAR CANCER, 2018, 卷号: 17
作者:  Ding, Chen-Hong;  Yin, Chuan;  Chen, Shi-Jie;  Wen, Liang-Zhi;  Ding, Kai
收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08
18glycyrrhetinicacidprotectsagainstalphanaphthylisothiocyanateinducedcholestasisthroughactivationofthesirt1fxrsignalingpathway 期刊论文
中国药理学报英文版, 2018, 卷号: 039, 期号: 012, 页码: 1865
作者:  Shouyan Wu;  Shichao Cui;  Le Wang
收藏  |  浏览/下载:3/0  |  提交时间:2020/07/01
18β-Glycyrrhetinic acid protects against alphanaphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway 期刊论文
Acta Pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1865
作者:  Wu Shouyan;  Cui Shichao;  Wang Le;  Zhang Yiting;  Yan Xiaoxia
收藏  |  浏览/下载:9/0  |  提交时间:2020/12/24
Chemical Cocktails Enable Hepatic Reprogramming of Mouse Fibroblasts with a Single Transcription Factor 期刊论文
STEM CELL REPORTS, 2017, 卷号: 9, 期号: 2, 页码: 499-512
作者:  Guo, Ren;  Tang, Wei;  Yuan, Qianting;  Hui, Lijian;  Wang, Xin
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08
Baicalin benefits the anti-HBV therapy via inhibiting HBV viral RNAs 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017, 卷号: 323
作者:  Huang, Hai;  Zhou, Wei;  Zhu, Haiyan;  Zhou, Pei;  Shi, Xunlong
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
Optimized Hepatocyte-Like Cells with Functional Drug Transporters Directly-Reprogrammed from Mouse Fibroblasts and their Potential in Drug Disposition and Toxicology 期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 卷号: 38, 期号: 5, 页码: 1815-1830
作者:  Wu, Zhi-Tao;  Yao, Dan;  Ji, Shu-Yi;  Ni, Xuan;  Gao, Yi-Meng
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
Apolipoprotein M 期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2015, 卷号: 446, 页码: 21-29
作者:  Ren, Kun;  Tang, Zhen-Li;  Jiang, Yue;  Tan, Yan-Mei;  Yi, Guang-Hui*
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/27
apo  apolipoprotein  HDL  high-density lipoprotein  HNF-1α,4α  hepatocyte nuclear factor-1α,4α  LRH-1  liver receptor homolog-1  Foxa2  forkhead box A2  PAF  platelet activating factor  LXR  liver X receptor  RXR  retinoid X receptor  FXR  farnesoid X receptor  SHP  small heterodimer partner  S1P  Sphingosine-1-Phosphate  CVD  cardiovascular disease  HDL-C  HDL cholesterol  RCT  reverse cholesterol transport  MHC  major histocompatibility complex class III  TNF  tumor necrosis factor  HRP  haptoglobin-related protein  PON-I  paraoxonase-1  SNP  single nucleotide polymorphism  T1,2D  type 1,2 diabetes  RA  rheumatoid arthritis  ABCA1  ATP-binding cassette transporter A1  PPAR-γ  peroxisome proliferator-activated receptor γ  IL  interleukin  ABCG  ATP-binding cassette sub-family G  CETP  cholesteryl ester transfer protein  SR-B1  scavenger receptor class B member 1  MODY3  maturity-onset diabetes of the young type 3  MUP  major urinary protein  RBP  retinol binding protein  RAR  retinoic acid receptor  TR  thyroid hormone receptor  PI3K  phosphatidylinositol 3-kinase  DHC  dihydrocapsaicin  HRE  hormone response element  IGF-1  insulin-like growth factors  PAF-R  platelet activating factor receptor  TGF-α,β  transforming growth factor-α,β  EGF  epidermal growth factor  HGF  hepatic growth factor  VLDL  very low-density lipoprotein  LDL  low-density lipoprotein  ldlr  LDL receptor  ldlr−/−  LDL-receptor deficient  LCAT  lecithin-cholesterol acyltransferase  CE  cholesteryl ester  TC  total cholesterol  LDL-C  LDL cholesterol  VLDL-C  VLDL cholesterol  CHD  coronary heart disease  Mets  metabolic syndrome  S1PR  S1P receptor  NF-κB  nuclear factor-κB  NO  nitrogen oxide  eNOS  endothelial nitric oxide synthase  apoM-TgN mice  mice overexpressing human apoM by approximately two-fold  apoM-TgH mice  mice overexpressing human apoM by approximately ten-fold  apoM−/− mice  apoM-null mice  apoE−/−  apoE-null mice  Apolipoprotein M  Regulation  Function  


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