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pCO2-driven seawater acidification affects aqueous-phase copper toxicity in juvenile flounder Paralichthys olivaceus: Metal accumulation, antioxidant defenses and detoxification in livers
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 858, 页码: 13
作者:
Xiao, Zitao
;
Cao, Liang
;
Liu, Jinhu
;
Cui, Wenting
;
Dou, Shuozeng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2023/12/13
Ocean acidification
Heavy metal
Marine fish
Oxidative stress
Biotransformation
Integrative response
Zinc oxide/graphene oxide nanocomposites efficiently inhibited cadmium-induced hepatotoxicity via releasing Zn ions and up-regulating MRP1 expression
期刊论文
ENVIRONMENT INTERNATIONAL, 2022, 卷号: 165
作者:
Liu, Yun
;
Wang, Xue
;
Si, Bo
;
Wang, Tong
;
Wu, Yun
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
Cadmium
Zinc oxide
Graphene oxide
Detoxification
Bioaccumulation
Magnetic resonance imaging
Case Report: Hepatic Sarcoid-Like Reaction Associated With Checkpoint Inhibition in a NSCLC Patient and a Literature Review
期刊论文
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12
作者:
Lin, Yuxin
;
Zhu, Wei
;
Wu, Bingchen
;
Lan, Huiyin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/05/16
Sarcoid-like reaction
immune checkpoint inhibitor
Toripalimab
PD-1
case report
Nano-selenium attenuates mitochondrial-associated apoptosis via the PI3K/AKT pathway in nickel-induced hepatotoxicity in vivo and in vitro
期刊论文
ENVIRONMENTAL TOXICOLOGY, 2021
作者:
Wang, Caixia
;
Gu, Zhangyu
;
Gu, Xueyan
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/11/01
hepatotoxicity
mitochondrial apoptosis
Nano-Se
nickel
PI3K-Akt pathway
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Simultaneous determination of monocrotaline and its N-oxide metabolite in rat plasma using LC-MS/MS: Application to a pharmacokinetic study
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2021, 页码: 7
作者:
Lin, Feifei
;
Pan, Anni
;
Ye, Yang
;
Liu, Jia
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/08/17
LC-MS
MS
monocrotaline
monocrotaline N-oxide
pharmacokinetics
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
Effects of dibutyl phthalate on lipid metabolism in liver and hepatocytes based on PPAR alpha/SREBP-1c/FAS/GPAT/AMPK signal pathway
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 149
作者:
Zhang, Wang
;
Li, Jing-Ya
;
Wei, Xiao-Chen
;
Wang, Qian
;
Yang, Ji-Yang
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/04/26
DBP
PPAR alpha
AMPK
Lipid metabolism
Liver function
Tetrabromobisphenol A (TBBPA): A controversial environmental pollutant
期刊论文
JOURNAL OF ENVIRONMENTAL SCIENCES, 2020, 卷号: 97, 页码: 54-66
作者:
Zhou, Hui
;
Yin, Nuoya
;
Faiola, Francesco
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/09/14
Tetrabromobisphenol A (TBBPA)
Developmental toxicity
Endocrine disrupting chemicals(EDC)
Hepatotoxicity
Neurotoxicity
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
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