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科研机构
合肥物质科学研究院 [9]
上海药物研究所 [8]
上海生物化学与细胞生... [2]
西安交通大学 [1]
深圳先进技术研究院 [1]
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期刊论文 [22]
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Circular RNA cMras Suppresses the Progression of Lung Adenocarcinoma Through ABHD5/ATGL Axis Using NF-kappa B Signaling Pathway
期刊论文
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2020
作者:
Zhou, Qinfei
;
Sun, Yan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/12/28
ABHD5
ATGL
circ_cMras
LAC
NF-κ
B signaling pathway
p53
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer (NSCLC)
EGFR T790M
Small-molecule inhibitor
Drug resistance
Ack1
Inhibition of Tumor Lymphangiogenesis is an Important Part that EGFR-TKIs Play in the Treatment of NSCLC
期刊论文
JOURNAL OF CANCER, 2020, 卷号: 11, 期号: 1, 页码: 241-250
作者:
Zhang, Yan
;
Yang, Xinying
;
Liu, Hongchun
;
Cai, Minghui
;
Yang Shentu
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
EGFR-TKIs
NSCLC
lymphangiogenesis
JAK/STAT3
LYVE-1
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met
期刊论文
CANCER SCIENCE, 2019, 页码: 11
作者:
Tong, Mengya
;
Gao, Mingzhao
;
Xu, Yongping
;
Fu, Li
;
Li, Yun
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
AZD9291
c-Met ADC
c-Met overexpression
resistance
SHR-A1403
[Mechanism of MALAT1 induced osimertinib resistance in HCC827 lung cancer cells].
期刊论文
Zhonghua zhong liu za zhi [Chinese journal of oncology], 2019, 卷号: 41, 期号: 4
作者:
Kang X H
;
Gao Y Y
;
Wang Y
;
Cui Y H
;
Zhao K L
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Epidermal growth factor receptor
Lung neoplasms
Metastasis associated in lung adenocarcinoma transcript
Osimertinib
Arsenic circumvents the gefitinib resistance by binding to P62 and mediating autophagic degradation of EGFR in non-small cell lung cancer
期刊论文
CELL DEATH & DISEASE, 2018, 卷号: 9
作者:
Mao, Jianhua
;
Ma, Lie
;
Shen, Yan
;
Zhu, Kongkai
;
Zhang, Ru
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/01/08
Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2944-2962
作者:
Wang, Aoli
;
Li, Xixiang
;
Wu, Hong
;
Zou, Fengming
;
Yan, Xiao-E
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2018/07/26
Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2944-2962
作者:
Wang, Aoli
;
Li, Xixiang
;
Wu, Hong
;
Zou, Fengming
;
Yan, Xiao-E
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2018/07/26
Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2944-2962
作者:
Wang, Aoli
;
Li, Xixiang
;
Wu, Hong
;
Zou, Fengming
;
Yan, Xiao-E
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2018/07/26
Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2944-2962
作者:
Wang, Aoli
;
Li, Xixiang
;
Wu, Hong
;
Zou, Fengming
;
Yan, Xiao-E
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2018/07/26
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