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浏览/检索结果:
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Global characterization of proteome and lysine methylome features in EZH2 wild-type and mutant lymphoma cell lines
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 213, 页码: 10
作者:
Hao, Bingbing
;
Sun, Mingwei
;
Zhang, Min
;
Zhao, Xiaoxiao
;
Zhao, Lei
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
Lysine methylome
Quantitative proteomics
EZH2
Diffuse large B cell lymphoma
PTM crosstalk
C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1457-1465
作者:
Shi, Yi
;
Ma, Hong-lei
;
Zhuang, You-wen
;
Wang, Xiao-xi
;
Jiang, Yi
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  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
PRC2
C10ORF12
H3K27me3
histone methyltransferase
epigenetic regulation
histone modification
Inhibition of Ezh2 In Vitro and the Decline of Ezh2 in Developing Midbrain Promote Dopaminergic Neurons Differentiation Through Modifying H3K27me3
期刊论文
STEM CELLS AND DEVELOPMENT, 2019, 卷号: 28, 期号: 10, 页码: 649-658
作者:
Hong, Feng
;
Zhao, Mengxue
;
Zhang, Lei
;
Feng, Linyin
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  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
dopaminergic neurons
Ezh2
Nurr1
neural stem cells
c10orf12modulatesprc2histonemethyltransferaseactivityandh3k27me3levels
期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 11, 页码: 1457
作者:
Shi Yi
;
Ma Honglei
;
Zhuang Youwen
;
Wang Xiaoxi
;
Jiang Yi
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
REPRESSIVE COMPLEX 2
GENOMIC TARGETS
POLYCOMB
PROTEIN
CHROMATIN
RECRUITMENT
JARID2
DIFFERENTIATION
BINDING
METHYLATION
PRC2
C10ORF12
H3K27me3
histone methyltransferase
epigenetic regulation
histone modification
Utx loss causes myeloid transformation
期刊论文
LEUKEMIA, 2018, 卷号: 32, 期号: 6, 页码: 1458-1465
作者:
Zheng, Liting
;
Xu, Longyong
;
Xu, Qing
;
Yu, Lu
;
Zhao, Danfeng
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/04/28
Chronic Myelomonocytic Leukemia
Acute Lymphoblastic-leukemia
H3k27me3 Demethylase Utx
Histone Lysine Demethylases
Tumor-suppressor
Spectrum Analysis
Methylation
Cancer
Mutations
Mice
Structure of the PRC2 complex and application to drug discovery
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 963-976
作者:
Shi, Yi
;
Wang, Xiao-xi
;
Zhuang, You-wen
;
Jiang, Yi
;
Melcher, Karsten
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
PRC2
histone methyltransferase
H3K27me3
nucleosome
structure
drug discovery
structureoftheprc2complexandapplicationtodrugdiscovery
期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 7, 页码: 963
作者:
Shi Yi
;
Wang Xiaoxi
;
Zhuang Youwen
;
Jiang Yi
;
Melcher Karsten
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/07/01
PRC2
histone methyltransferase
H3K27me3
nucleosome
structure
drug discovery
Identification of novel ezh2 inhibitors through pharmacophore-based virtual screening and biological assays
期刊论文
Bioorganic & medicinal chemistry letters, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:
Wu, Yunlong
;
Hu, Junchi
;
Ding, Hong
;
Chen, Limin
;
Zhang, Yuanyuan
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/05/09
Ezh2
Epigenetics
Prc2
Computational drug design
Pharmacophore-based virtual screening
Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:
Wu, Yunlong
;
Hu, Junchi
;
Ding, Hong
;
Chen, Limin
;
Zhang, Yuanyuan
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
EZH2
Epigenetics
PRC2
Computational drug design
Pharmacophore-based virtual screening
miR-214 protects erythroid cells against oxidative stress by targeting ATF4 and EZH2
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2016, 卷号: 92, 期号: 0, 页码: 39-49
作者:
Gao, Ming
;
Liu, Yun
;
Chen, Yue
;
Yin, Chunyang
;
Chen, Jane-Jane
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2017/03/27
miR-214
Nrf2
ATF4
EZH2
Erythroid cells
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