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浏览/检索结果: 共9条，第1-9条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586 作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang 收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01 JAK/STAT  3-deoxy-2 beta,16-dihydroxynagilactone E  tyrosine kinase inhibitor  allosteric inhibitor  cancer   Xanthatin inhibits STAT3 and NF-kappa B signalling by covalently binding to JAK and IKK kinases 期刊论文 JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 6, 页码: 4301-4312 作者:  Liu, Man;  Xiao, Cheng-qian;  Sun, Ming-wei;  Tan, Min-jia;  Hu, Li-hong 收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01 covalent interaction  IKK inhibitor  JAK inhibitor  natural compound   3deoxy216dihydroxynagilactoneeanaturalcompoundfrompodocarpusnagipreferentiallyinhibitsjak2stat3signalingbyallostericallyinteractingwiththeregulatorydomainofjak2andinducesapoptosisofcancercells 期刊论文 actapharmacologicasinica, 2019, 卷号: 40, 期号: 12, 页码: 1578 作者:  Shan Hui;  Yao Sheng;  Ye Yang;  Yu Qiang 收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01 JAK/STAT  3-deoxy-2β  16-dihydroxynagilactone E  tyrosine kinase inhibitor  allosteric inhibitor  cancer   3-Deoxy-2β,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/ STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文 中国药理学报:英文版, 2019, 卷号: 40.0, 期号: 012, 页码: 1578 作者:  Hui Shan;  Sheng Yao;  Yang Ye;  Qiang Yu 收藏  |  浏览/下载：17/0  |  提交时间：2020/12/24 JAK/STAT  3-deoxy-2β,16-dihydroxynagilactone  E  tyrosine  kinase  inhibitor  allosteric  inhibitor  cancer   A phosphatidylinositol 4,5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing 期刊论文 NATURE COMMUNICATIONS, 2018, 卷号: 9, 页码: 16 作者:  Mu, Libing;  Tu, Zhongyuan;  Miao, Lin;  Ruan, Hefei;  Kang, Ning 收藏  |  浏览/下载：97/0  |  提交时间：2018/12/04 Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases 期刊论文 MOLECULES, 2018, 卷号: 23, 期号: 6 作者:  Liu, Man;  Xiao, Chengqian;  Sun, Mingwei;  Tan, Minjia;  Hu, Lihong 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 parthenolide  covalent inhibitor  cell death  JAK/STAT3 signaling   Structural study on two tandem helix bundles of the rod domain of talin, an integrin activator 期刊论文 Progress in biochemistry and biophysics, 2015, 卷号: 42, 期号: 6, 页码: 574-582 作者:  Lin Lin;  Song Xian-Qiang;  Ye Sheng;  Zhang Rong-Guang 收藏  |  浏览/下载：22/0  |  提交时间：2019/05/10 Talin  R9-10  R10-11  Crystal structure  Tandem helix bundles  Auto-inhibition   A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion 期刊论文 CELL RESEARCH, 2012, 卷号: 22, 期号: 11, 页码: 1533-1545 Song, Xianqiang; Yang, Jun; Hirbawi, Jamila; Ye, Sheng; Perera, H Dhanuja; Goksoy, Esen; Dwivedi, Pallavi; Plow, Edward F; Zhang, Rongguang; 张荣光; Qin, Jun 收藏  |  浏览/下载：13/0  |  提交时间：2013/12/24 cell adhesion  FERM domain  integrin signaling  crystallography  NMR   Pull and push: Talin activation for integrin signaling 期刊论文 细胞研究英文版, 2012 Wang, Jia-huai 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/13 STRUCTURAL BASIS  DOMAIN  TAIL