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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo
期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:
Sun, Hao
;
Bai, Xiaoyi
;
Zhang, Yiting
;
Gao, Yanan
;
Dai, Jiajia
收藏
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浏览/下载:0/0
  |  
提交时间:2024/06/04
Anti-tumor
SHP2
Orthosteric inhibitor
Apoptosis
Bromophenol
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:
Hua, Chen
;
Shena, Lijuan
;
Zoua, Fengming
;
Wua, Yun
;
Wanga, Beilei
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  |  
浏览/下载:11/0
  |  
提交时间:2023/11/10
Acquired resistance mutations
CDK9 inhibitors
Transcription
Single nucleotide polymorphisms
BAY1251152
Wnt Signaling Pathway Collapse upon beta-Catenin Destruction by a Novel Antimicrobial Peptide SKACP003: Unveiling the Molecular Mechanism and Genetic Activities Using Breast Cancer Cell Lines
期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 3, 页码: 1
作者:
Selvarathinam, Kanitha
;
Subramani, Prabhu
;
Thekkumalai, Malarvili
;
Vilwanathan, Ravikumar
;
Selvarajan, Ramganesh
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/14
antimicrobial peptides
anticancer agents
breast cancer
Wnt pathway
beta-catenin
downregulation
oncology
alternative therapy
Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Anti-tumor Activity of Disulfiram and Cisplatin in Ovarian Cancer
期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23
作者:
Du, Ruiping
;
Sun, Feilong
;
Li, Kai
;
Qi, Jian
;
Zhong, Wen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/10
Disulfiram
cisplatin resistance
ovarian cancer
proteomics analysis
SMAD3
lactate dehydrogenase
Simulating androgen receptor selection in designer yeast
期刊论文
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022, 卷号: 7
作者:
Zhang, Haoran
;
Zhang, Lu
;
Xu, Yipeng
;
Chen, Shaoyong
;
Ma, Zhenyi
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  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
Androgen receptor mutations
Androgen receptor antagonists
Prostate cancer
Saccharomyces cerevisiae
Fucoidan, as an immunostimulator promotes M1 macrophage differentiation and enhances the chemotherapeutic sensitivity of capecitabine in colon cancer
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 222, 页码: 562-572
作者:
Deng, Zhenzhen
;
Wu, Ning
;
Suo, Qishan
;
Wang, Jing
;
Yue, Yang
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/01/04
Capecitabine
Tumor microenvironment
Macrophages
TLR4
Fucoidan
The reversal of anti-HER2 resistance in advanced HER2-positive breast cancer using apatinib: two cases reports and literature review
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2022
作者:
He, Libin
;
Shen, Xiabo
;
Liu, Yiyuan
;
Gao, Lu
;
Wu, Jiayi
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
Advanced human epidermal growth factor receptor 2-positive breast cancer (advanced HER2-positive breast cancer)
apatinib
case report
Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors
期刊论文
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:
Zhang,Pei
;
Du,Yang
;
Bai,Hua
;
Wang,Zhijie
;
Duan,Jianchun
收藏
  |  
浏览/下载:123/0
  |  
提交时间:2022/11/21
Tucidinostat
Tumor microenvironment
PD-L1
CCL5
Solid tumor
Effects of Sensitized Sorafenib with a Paeoniflorin and Geniposide Mixture on Liver Cancer via the NF-kappa B-HIF-2 alpha-SerpinB3 Pathway
期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2022, 卷号: 2022
作者:
Li, Jun-Fei
;
Zheng, Xiao-Rong
;
Zhang, Hong-Yan
;
Shen, Chang-Ming
;
Shen, Guo-xin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/23
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