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上海药物研究所 [3]
中国医学科学院 北京... [3]
南华大学 [2]
清华大学 [2]
武汉大学 [2]
复旦大学上海医学院 [2]
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期刊论文 [18]
专利 [1]
会议论文 [1]
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2019 [3]
2018 [3]
2015 [1]
2014 [3]
2013 [2]
2012 [1]
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Immunology [1]
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Dexamethasone combined with berberine is an effective therapy for bleomycin-induced pulmonary fibrosis in rats
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 18, 期号: 4
作者:
Shen, Yanhua
;
Liu, Fangying
;
Ma, Wei
;
Wang, Zhongfu
;
Wei, Lei
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/12/05
pulmonary fibrosis
bleomycin
berberine plus dexamethasone
CXC chemokine ligand 14
matrix metalloproteinase 2
matrix metalloproteinase 9
Smad2
3
Mechanism of Cxc Chemokine Ligand 5 (CXCL5)/Cxc Chemokine Receptor 2 (CXCR2) Bio-Axis in Mice with Acute Respiratory Distress Syndrome
期刊论文
MEDICAL SCIENCE MONITOR, 2019, 卷号: 25
作者:
Wang, Chang-yong
;
Shang, Min
;
Zhou, Chen-liang
;
Feng, Li-zhi
;
Zhou, Qing-shan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Chemokine CXCL5
Inflammation
Respiratory Distress Syndrome, Adult
CXC chemokine ligand 12 (CXCL12) in atherosclerosis: An underlying therapeutic target.
期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2019, 卷号: 495, 页码: 538-544
作者:
Gao, Jia-Hui
;
Yu, Xiao-Hua
;
Tang, Chao-Ke*
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/27
Atherosclerosis
CXCL12
CXCR4
CXCR7
Ligand-based pharmacophore model for the discovery of novel CXCR2 antagonists as anti-cancer metastatic agents
期刊论文
ROYAL SOCIETY OPEN SCIENCE, 2018, 卷号: 5, 期号: 7
作者:
Che, Jinxin
;
Wang, Zhilong
;
Sheng, Haichao
;
Huang, Feng
;
Dong, Xiaowu
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
pharmacophore model
CXCR2
antagonists
anti-cancer metastasis
The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 149, 页码: 148-169
作者:
Peng, Dian
;
Cao, Bin
;
Zhou, Ying-Jun
;
Long, Ya-Qiu
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
CXC chemokine receptor 4
Small molecule antagonists
Structure-based optimization
HIV-1 entry
Tumor metastasis
Inflammation
Ischemia-reperfusion
Autoimmune
High CXC Chemokine Ligand 16 (CXCL16) Expression Promotes Proliferation and Metastasis of Lung Cancer via Regulating the NF-kappa B Pathway
期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24
作者:
Liang, Kun
;
Liu, Yanru
;
Eer, Dun
;
Liu, Jingbin
;
Yang, Fan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Cell Proliferation
Chemokines
CXC
Lung Neoplasms
Neoplasm Invasiveness
NF-kappa B
Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis
期刊论文
The International Journal of Biochemistry & Cell Biology, 2015, 卷号: 67, 页码: 92-100
作者:
Luo, Yangyang
;
Wang, Yong
;
Shu, Ye
;
Lu, Qianjin
;
Xiao, Rong*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
SSc
systemic sclerosis
SRC
scleroderma renal crisis
PAH
pulmonary arterial hypertension
SMR
standardized mortality ratio
DNMTs
DNA methyltransferases
SAM
S-adenosyl-methionine
5mC
5-methylcytosine
MBD
methyl-CpG-binding domain
Tet
ten–eleven translocation
HATs
histone acetyltransferases
HDACs
histone deacetylases
MiRNAs
microRNAs
MZ
monozygotic
DZ
dizygotic
MVECs
microvascular endothelial cells
FBs
fibroblasts
JAMs
junctional adhesion molecules
CTGF
connective tissue growth facto
TGF-β
transforming growth factor beta
CCN2
connective tissue growth factor
Fli1
Friend leukemia integration-1
TF
transcription factor
PECAM
platelet/endothelial cell adhesion molecule
PDGF
platelet derived growth factor
S1P1
sphingosin 1 phosphate
CXCL5
CXC chemokine ligand-5
BMPs
bone morphogenetic proteins
BMPRII
bone morphogenetic protein type II receptor
ET-1
endotheline-1
uPA
urokinase-type plasminogen activator
MBD
methyl-CpG-binding domain protein
ICAM
intercellular adhesion molecule
KLF5
Kruppel-like factor 5
Tregs
regulatory T cells
Runx1
Runt-related transcription factor 1
FOXP3
forkhead box protein 3 gene
ECM
extra cellular matrix
PDGF
platelet-derived growth factor
dSSc
diffuse systemic sclerosis
lSSc
limited systemic sclerosis
PCAF
protein-associated factor
Egr-1
early growth response 1
DDR2
discoidin domain receptor 2
TAB1
TGF-β activated kinase 1 binding protein 1
BAFF
B cell-activating factor
TSP-2
thrombospondin-2
MRTSS
Modified Rodnan total skin score
SDAI
Valentini scleroderma disease activity index
HC
healthy controls
SLE
systemic lupus erythematosus
SSD
scleroderma spectrum disorder
MTX
methylaminopterin
CYC
cyclophosphamide
MMF
mycophenolate mofetil
ACE
angiotensin converting enzyme
NO
nitric oxide
Systemic sclerosis
Epigenetic mechanisms
Biomarker
Therapy
Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2014, 卷号: 33
作者:
Zhao, Shengqiang
;
Wang, Jing
;
Qin, Chengyong
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/17
Intrahepatic cholangiocarcinoma (IHCC)
CXC chemokine ligand-12
(CXCL12)/chemokine receptor type 4 (CXCR4)
Prognosis
Metastasis
Wnt
pathway
Increased levels of plasma CXC-Chemokine Ligand 10, 12 and 16 are associated with right ventricular function in patients with idiopathic pulmonary arterial hypertension
期刊论文
2014, 卷号: 43, 期号: 4, 页码: 322-327
作者:
Yang, Tao
;
Li, Zhen-Nan
;
Chen, Guo
;
Gu, Qing
;
Ni, Xin-Hai
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/13
CXC-chemokine ligand
Pulmonary arterial hypertension
Right ventricular function
Biomarkers
Interleukin-17A in lipid metabolism and atherosclerosis
期刊论文
Clinica Chimica Acta, 2014, 卷号: 431, 页码: 33-39
作者:
Yu, Xiao-Hua
;
Jiang, Na
;
Zheng, Xi-Long
;
Cayabyab, Francisco S
;
Tang, Zhi-Bin*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
IL-17
interleukin-17
Th17
T helper 17
IL-17R
IL-17 receptor
STAT3
signal transducer and activator of transcription 3
RORγ
retinoic acid receptor-related orphan receptor γ
IRF4
interferon regulatory factor 4
ERK
extracellular signal-regulated kinase
Ets1
E26 transformation-specific 1
15(S)-HETE
15(S)-hydroxyeicosatetraenoic acid
SF1
alternative splicing factor
MAPK
mitogen-activated protein kinase
PPARγ
peroxisome proliferator-activated receptor γ
TRAF
tumor necrosis factor receptor-associated factor
TAK1
transforming growth factor-β-activated kinase 1
TAB
TAK1-binding protein
IKK
IκB kinase
NF-κB
nuclear factor kappa-B
IKKi
inducible IKK
JNK
c-Jun N-terminal kinase
C/EBP
CCAAT/enhancer-binding protein
AP1
activator protein 1
USP
ubiquitin-specific protease
CXCL
CXC chemokine ligand
ASF
alternative splicing factor
Hsp90
heat shock protein 90
RCT
reverse cholesterol transport
ABCA1
ATP-binding cassette transporter A1
apo E
apolipoprotein E
LDLR
low-density lipoprotein receptor
FABP4
fatty acid-binding protein-4
IL-17A
IL-17RA
IL-17RC
Lipid metabolism
Atherosclerosis
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