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浏览/检索结果:
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Simulating androgen receptor selection in designer yeast
期刊论文
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022, 卷号: 7
作者:
Zhang, Haoran
;
Zhang, Lu
;
Xu, Yipeng
;
Chen, Shaoyong
;
Ma, Zhenyi
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
Androgen receptor mutations
Androgen receptor antagonists
Prostate cancer
Saccharomyces cerevisiae
Evaluation of the Estrogenic/Antiestrogenic Activities of Perfluoroalkyl Substances and Their Interactions with the Human Estrogen Receptor by Combining In Vitro Assays and In Silico Modeling
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 22, 页码: 14514-14524
作者:
Li, Juan
;
Cao, Huiming
;
Feng, Hongru
;
Xue, Qiao
;
Zhang, Aiqian
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/09/14
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Mechanistic in silico modeling of bisphenols to predict estrogen and glucocorticoid disrupting potentials
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 728, 页码: 1-11
作者:
Chen, Qinchang
;
Zhou, Chengzhuo
;
Shi, Wei
;
Wang, Xiaoxiang
;
Xia, Pu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/09/14
Endocrine disruptor
Estrogen receptor
Glucocorticoid receptor
Coregulators
Accelerated molecular dynamics simulations
Binding free energy
A molecular switch regulating transcriptional repression and activation of PPAR gamma
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 14
作者:
Shang, Jinsai
;
Mosure, Sarah A.
;
Zheng, Jie
;
Brust, Richard
;
Bass, Jared
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:
Zhang, Feng-cai
;
Sun, Zhong-ya
;
Liao, Li-ping
;
Zuo, Yu
;
Zhang, Dan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
Protonation state effects of estrogen receptor alpha on the recognition mechanisms by perfluorooctanoic acid and perfluorooctane sulfonate: A computational study
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 171, 页码: 647-656
作者:
Cao, Huiming
;
Wang, Ling
;
Liang, Yong
;
Li, Zhunjie
;
Feng, Hongru
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/10/21
Estrogen receptor alpha
Perfluorooctanoic acid
Perfluorooctane sulfonate
Protonation state
Molecular dynamics simulations
Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2019, 卷号: 59, 期号: 2, 页码: 842-857
作者:
Hou, Tingjun
;
Li, Youyong
;
Yu, Huidong
;
Li, Dan
;
Liu, Hui
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/06/24
Verification of osteoblast differentiation on airborne-particle abrasion, large-grit, acid-etched surface of titanium implants regulated by yes-associated protein and transcriptional coactivator with PDZ-binding motif
期刊论文
JOURNAL OF ORAL SCIENCE, 2019, 卷号: 61, 期号: 3, 页码: 431-440
作者:
Wei, Ting
;
Li, Jiayi
;
Sun, Huiqiang
;
Jiang, Mengyang
;
Yang, Yun
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
SLA Ti implant
YAP
TAZ
MC3T3-E1 cell
osseointegration
Effect of 1, 25-dihydroxyvitamin D3 on the osteogenic differentiation of human periodontal ligament stem cells and the underlying regulatory mechanism
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2019, 卷号: 43, 期号: 1, 页码: 167-176
作者:
Ji, Yawen
;
Zhang, Panpan
;
Xing, Yixiao
;
Jia, Linglu
;
Zhang, Yunpeng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
human periodontal ligament stem cells
1
25-dihydroxyvitamin D3
osteogenic differentiation
Hippo pathway
transcriptional coactivator
with the PDZ-binding motif
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